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We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 170 start-ups with an aggregate funding of $4.5b. The average funding per company in this subset is $64.6m.

Last update to the database: Feb 18, 2025. See changelog.

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10

Funding Rounds

$930.0m

Money raised

Tempus, a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

6

Funding Rounds

$303.0m

Money raised

VAST Data is a developer of a data storage platform designed to manage storage software unlocking the value of data and modernizing data centers in preparation for the era of AI computing.

Key people:

5

Funding Rounds

$103.1m

Money raised

Promethera Biosciences is a biotechnology company developing regenerative medicine treatments for liver diseases.

4

Funding Rounds

$150.0m

Money raised

Net Power is a Durham, North Carolina-based natural gas electricity producer using carbon capture and storage to maintain zero emissions production.

2

Funding Rounds

$67.5m

Money raised

A company developing immunotherapy treatments for cancers, infectious and autoimmune diseases

2

Funding Rounds

$12.8m

Money raised

Developer of a healthcare platform designed to simplify personal health data. The company's platform captures data from clinical and remote-monitoring devices, sensors, fitness equipment, and patient-wellness applications, enabling users to access, manage and utilize device-generated data.

4

Funding Rounds

$13.9m

Money raised

Genecentric Diagnostics, Inc. is an oncology diagnostic and treatment center.

1

Funding Rounds

$21.0m

Money raised

A company that cultures human mammary cells and produces custom and commercial lab-grown breastmilk. It was founded in 2020 and is located in Durham, North Carolina.

Key people:

2

Funding Rounds

$6.2m

Money raised

A biotechnology company with a focus on developing medical solutions with biomaterial. It was founded in 2015 and is located in Durham, North Carolina.

Key people:

2

Funding Rounds

$83.0m

Money raised

bioMASON's is a company that uses organisms to grow biocementTM based construction materials.

Key people:

12

Funding Rounds

$273.6m

Money raised

Vestaron is a Kalamazoo, Michigan-based agricultural technology company manufacturing bioinsecticides from naturally occurring peptides

3

Funding Rounds

$10.7m

Money raised

Suite of APIs that help brands build custom ad platforms.

5

Funding Rounds

$78.0m

Money raised

CloudFactory is an outsourcing company offering human-powered data processing services for artificial intelligence and automation companies.

7

Funding Rounds

$252.5m

Money raised

AgBiome is focused on the discovery and development of biological and trait products for crop production.

6

Funding Rounds

$80.4m

Money raised

Spreedly is the last payments API you'll ever need: - Cut PCI risk and boost flexibility with secure card capture and storage - Connect once, integrate with 220+ payment services - Drive more business, in more markets, with more partners See how you can start today: https://www.spreedly.com Spreedly provides cloud-based PCI Level-1 infrastructure for payments software. Businesses use Spreedly to connect to multiple payment gateways, payment receivers, and a secure credit card vault - all through a single API. That enables our customers to do more business, in more markets, with more partners - all while minimizing PCI compliance scope.

4

Funding Rounds

$41.7m

Money raised

Baebies, Inc. is a Durham, North Carolina-based medical diagnostics company delivering products and services for newborn screening and pediatric testing founded in 2013.

5

Funding Rounds

$21.0m

Money raised

Kevel offers the infrastructure APIs needed to build custom ad platforms for sponsored listings, internal promotions, native ads, and more.

6

Funding Rounds

$25.3m

Money raised

Credible is a student loan marketplace founded in 2012 by Stephen Dash.

4

Funding Rounds

$10.8m

Money raised

Automated Insights is a Durham, North Carolina-based company offering content automation services and founded in 2007 by Robbie Allen.

3

Funding Rounds

$8.0m

Money raised

ReverbNation is a website that is meant to connect artists to the music industry

5

Funding Rounds

$66.9m

Money raised

restor3d enables surgeons to improve the reconstruction and repair of the human body through 3D printed implants with enhanced anatomical fit and superior integrative properties.

5

Funding Rounds

$48.3m

Money raised

Sense Photonics is a company building LiDAR and 3D sensor solutions for autonomous vehicles, industrial robotics, material handling, activity monitoring, and other applications.

1

Funding Rounds

$23.1m

Money raised

NeuroTronik is a company that develops neurostimulation therapeutic devices which are designed to treat acute heart failure syndrome.

1

Funding Rounds

$3.0m

Money raised

LoanWell is a End-to-End platform for Lenders with Intake, Origination, Underwriting, Closing, Servicing, & Reporting all in one platform. Our system can be completely branded and customized (like Squarespace) and is specifically designed with flexibility in mind for the multi-faceted origination and servicing needs of Lenders.

2

Funding Rounds

$115.0m

Money raised

Pairwise uses CRISPR, gene editing and natural diversity in agricultural crops to address global food challenges. The company is working to develop new varieties of crops.

1

Funding Rounds

$1.6m

Money raised

We use land-first models to provide mass appraisal modeling and property valuations with unparalleled accuracy.

3

Funding Rounds

$8.3m

Money raised

First is a Durham, North Carolina-based company founded in 1968 by Jess Martin.

2

Funding Rounds

$70.0m

Money raised

Eleanor Health is a healthcare company founded by Corbin Petro.

4

Funding Rounds

$2.0m

Money raised

celldom is a single cell omics company founded in 2016 by Zach Forbes, Benjamin Yellen and Kris Wood.

5

Funding Rounds

$23.3m

Money raised

Parion Sciences is a mucosal Targets founded in 2000.

3

Funding Rounds

$90.4m

Money raised

PlantResponse is a biotechnology company developing soil health solutions and products for crop nutrition.

1

Funding Rounds

$250.0k

Money raised

Polaris Quantum Biotech, Inc. is a company that combines machine learning, quantum computing, hybrid quantum and molecular mechanics simulations to help biotech companies discover drugs.

3

Funding Rounds

$97.2m

Money raised

StrideBio is a Durham, North Carolina-based company.

3

Funding Rounds

$7.0m

Money raised

kelaHealth is a company founded in 2016 by Prabath Peiris, Erich S. Huang, Jeff Sun and Bora Chang.

2

Funding Rounds

$53.1m

Money raised

ArchiveSocial is a Durham, North Carolina-based company founded in 2011 by Anil Chawla.

4

Funding Rounds

$52.8m

Money raised

Small molecule drugs that target functional 3D RNA structures to treat human diseases.

3

Funding Rounds

$11.4m

Money raised

Bayshore Networks is a company that provides cyber protection for the Industrial control systems, IoT.

1

Funding Rounds

$3.0m

Money raised

A company developing application-specific coatings and medical devices for the orthopedic and cardiovascular fields

3

Funding Rounds

$1.2m

Money raised

Biomedomics is a Durham, North Carolina-based developer of diagnostics solutions and tests for clinical and point-of-care situations.

1

Funding Rounds

$6.0m

Money raised

Banyan Biomarkers is a San Diego-based company developing and commercializing biomarkers to diagnose traumatic brain injuries. The company was acquired by bioMerieux in April 2018.

3

Funding Rounds

$92.0m

Money raised

Micro-organosphere technologies to guide precision therapy for cancer patients

1

Funding Rounds

$1.0m

Money raised

PlotWatt helps small-and medium-sized business owners manage their energy so they have energy to manage their businesses.

1

Funding Rounds

$168.0k

Money raised

medlio is a company founded in 2013 by Lori Mehen, David S. Brooks and Ravi Ada.

5

Funding Rounds

$161.3m

Money raised

Teamworks is a company founded by Zach Maurides.

2

Funding Rounds

$29.4m

Money raised

Nextreme Thermal Solutions provides thermal management solutions to varying areas of the global market.

3

Funding Rounds

$120.0m

Money raised

Company providing cooling and heating solutions based on solid-state phononic chips.

Industries:

Key people:

2

Funding Rounds

$63.1m

Money raised

Atsena Therapeutics, Inc. is a gene Therapy founded in 2019.

4

Funding Rounds

$4.5m

Money raised

GoldenKey is a company founded in 2014 by Tommy Sowers.

3

Funding Rounds

$88.9m

Money raised

Invaio is a Cambridge, Massachusetts-based biotechnology company founded by Ignacio Martinez.

1

Funding Rounds

$1.0m

Money raised

MindSumo is a company founded in 2011 by Keaton Swett, Trent Hazy and Rohan Puranik.

3

Funding Rounds

$249.6m

Money raised

4G Clinical is a clinical Trial Software founded in 2015 by Rob Campanella, David Kelleher and Ed Tourtellotte.

Key people:

7

Funding Rounds

$27.6m

Money raised

410 Medical Inc is an emergency Infusion Device founded in 2013.

4

Funding Rounds

$2.8m

Money raised

Trill A.I. is a company founded by Simon Jung.

3

Funding Rounds

$20.0m

Money raised

Hi Fidelity Genetics is a company founded in 2014 by Philip Benfey.

7

Funding Rounds

$70.0m

Money raised

Get Spiffy, Inc is a cleaning company founded in 2014 by Karl Murphy.

Industries:

Key people:

1

Funding Rounds

$11.0m

Money raised

A company developing diagnostic products to cure on-farm animal diseases

2

Funding Rounds

$22.0m

Money raised

A medical device company that develops cardiovascular drug-delivery systems

1

Funding Rounds

$220.0k

Money raised

ColoWrap is a colonoscopy medical device company founded in 2011 by James Hathorn.

Key people:

1

Funding Rounds

$200.0m

Money raised

Dermavant Sciences is a small Molecules for Dermatology Indications founded in 2016.

3

Funding Rounds

$2.5m

Money raised

PRSONAS, Inc. is an Artificial Intelligence company that develops software solutions.

Key people:

2

Funding Rounds

$1.2m

Money raised

inSoma Bio, Inc. is a tissue Reconstruction founded in 2018 by Ashutosh Chilkoti, Mindaugas Vaitkus, Stefan Roberts and Scott Hollenbeck.

Key people:

3

Funding Rounds

$30.4m

Money raised

T3D Therapeutics is a company developing drug therapy for Alzheimer's disease founded by John Didsbury.

Key people:

1

Funding Rounds

$12.7m

Money raised

Cell Microsystems is a North Carolina-based company developing, manufacturing, and marketing products for single-cell biology.

2

Funding Rounds

$19.5m

Money raised

FoodLogiQ offers Software as a Service solutions to connect the world's food supply chain, promoting food safety through traceability and sustainability.

2

Funding Rounds

$1.6m

Money raised

Argyle Social is a company founded in 2010.

2

Funding Rounds

$10.0m

Money raised

Curie Co is a company founded in 2017.

3

Funding Rounds

$5.8m

Money raised

CureMint is a Durham, North Carolina-based company founded in 2017 by Brandon Patrick McCarty.

2

Funding Rounds

$27.4m

Money raised

A company developing regenerative medicines for wound care, inflammation and angiogenesis

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