69 Best Machine Learning Startups in San Francisco to Watch in 2025

The Definitive Seedtable Ranking of Machine Learning Startups in San Francisco

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 327 start-ups with an aggregate funding of $70.4b. The average funding per company in this subset is $1.0b.

Last update to the database: Feb 18, 2025. See changelog.

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8

Funding Rounds

$58.2b

Money raised

OpenAI is an AI research and deployment platform.

Location:

Key people:

3

Funding Rounds

$364.2m

Money raised

Neuralink is a company that develops brain-computer interface (BCI) devices to assist people with paralysis and blindness and technologies that may expand the abilities of humans.

Location:

Key people:

3

Funding Rounds

$17.5m

Money raised

Numerai is a hedge fund with stock market trades determined by crowdsourced artificial intelligence models. The best models receive rewards in the form of a cryptographic token called Numeraire (NMR) on the Ethereum blockchain.

4

Funding Rounds

$74.3m

Money raised

Pachama is a company estimating carbon storage in forests and predicting future deforestation or potential for forest restoration with the use of satellite images.

4

Funding Rounds

$204.7m

Money raised

Primer is a San Francisco-based company developing AI to generate written intelligence reports.

3

Funding Rounds

$47.0m

Money raised

Paravision is a San Francisco-based provider of facial recognition and activity monitoring software. Paravision was previously known as Ever AI.

Location:

Key people:

4

Funding Rounds

$43.9m

Money raised

Iterative.ai is a machine learning and artificial intelligence training platform provider.

6

Funding Rounds

$775.6m

Money raised

Scale AI is an artificial intelligence company making an API for validating and training data for applications.

3

Funding Rounds

$21.0m

Money raised

Kite.Com is a San Francisco-based company that builds AI-powered auto-complete features for developers.

4

Funding Rounds

$92.0m

Money raised

Forethought is a San Francisco-based company providing customer service automation using generative AI technology.

Key people:

6

Funding Rounds

$215.0m

Money raised

Tecton is a machine learning DevOps platform for data scientists.

Location:

Key people:

8

Funding Rounds

$3.0b

Money raised

Postmates is a food delivery service company operating a network of couriers for local goods delivery.

2

Funding Rounds

$415.0m

Money raised

Adept AI Labs is a machine learning research and product lab building general intelligence systems

Location:

Key people:

7

Funding Rounds

$207.3m

Money raised

Replit is a San Francisco-based IDE and software development environment company making a browser application platform for coding in over fifty programming languages.

Location:

Key people:

6

Funding Rounds

$30.0m

Money raised

Rain AI is a company developing a new AI compute platform by co-designing every layer of the AI stack.

6

Funding Rounds

$53.9m

Money raised

Sight Machine's manufacturing software platform uses an artificial intelligence (AI) platform to help improve quality and efficiency across a manufacturing enterprise.

4

Funding Rounds

$20.0m

Money raised

A company offering an audio word processing platform that enables editor and producers to edit sound files while a writer would edit its lyrics.

Location:

Key people:

3

Funding Rounds

$113.0m

Money raised

Zilliz is a vector database company providing products for enterprise-grade AI.

4

Funding Rounds

$160.0m

Money raised

Suki is a Redwood City, California-based technology company developing AI-powered administrative tools for the healthcare industry.

3

Funding Rounds

$26.6m

Money raised

Wispr is a personal computing platform for an AI-first world.

5

Funding Rounds

$490.0m

Money raised

Grammarly is a web application for checking spelling, grammar, and plagiarism.

Location:

Key people:

3

Funding Rounds

$67.3m

Money raised

Luma AI is a developer of photorealistic 3D image capture software designed to enable users to capture 3D-viewable photos of scenes and objects on smartphones.

6

Funding Rounds

$214.0m

Money raised

Observe.AI is the creator of an AI platform for call centers.

4

Funding Rounds

$159.0m

Money raised

Aera Technology is a software company offering business automation functions.

4

Funding Rounds

$3.2m

Money raised

MonkeyLearn is an artificial intelligence data analysis and visualization platform.

4

Funding Rounds

$188.9m

Money raised

Labelbox is a training data platform with labeling tools, human workforce, data management, API, and automation features for computer vision.

7

Funding Rounds

$30.3m

Money raised

Mattermark is a San Francisco-based company founded by Kevin Morrill, Danielle Morrill and Andy Sparks.

Key people:

5

Funding Rounds

$162.5m

Money raised

A company offering a communications platform allows developers to quickly build features that connect to every email, calendar, and contacts provider in the world.

1

Funding Rounds

$12.0m

Money raised

Amplemarket provides lead generation, email outreach, and lead qualification on autopilot.

Key people:

8

Funding Rounds

$427.9m

Money raised

Standard AI is a software company creating autonomous checkout systems for retailers.

3

Funding Rounds

$20.0m

Money raised

You.com is an ad-free, private search engine.

Location:

Key people:

6

Funding Rounds

$220.5m

Money raised

Domino Data Lab is a machine learning platform enabling data science teams to rapidly develop and deploy models that drive breakthrough innovation

Location:

Key people:

5

Funding Rounds

$108.1m

Money raised

AssemblyAI is a speech AI company developing AI models capable of transcribing and understanding human speech.

4

Funding Rounds

$75.1m

Money raised

Volansi was a company offering delivery service for time-critical shipments using high-speed long-range drones. Volansi was acquired by Sierra Nevada Corporation in October 2022.

10

Funding Rounds

$704.5m

Money raised

Zipline is an automated logistics company that designs, manufactures, and delivers medical products.

Industries:

Key people:

1

Funding Rounds

$9.4m

Money raised

Datatron is an artificial Intelligence company providing machine learning, artificial intelligence, and data science models for user models.

2

Funding Rounds

$10.6m

Money raised

MindsDB is a Berkeley, California-based developer of machine learning capabilities capable of being integrated into databases.

1

Funding Rounds

$2.0m

Money raised

Cardiogram is a company building a personal healthcare assistant, using Deep Learning to turn consumer wearables into continuous health monitors. Cariogram can now detect 4 medical conditions Sleep Apnea, High Blood Pressure, Atrial Fibrillation, and Diabetes.

Location:

Key people:

5

Funding Rounds

$120.7m

Money raised

Hive is an artificial intelligence software company specializing in deep learning and computer vision.

Location:

Key people:

7

Funding Rounds

$64.3m

Money raised

Casetext is an AI legal research technology company. It was acquired by Thomson Reuters Corporation in June 2023.

3

Funding Rounds

$2.9m

Money raised

Artificial Intelligence company using Augmented Reality for collaborative professional services

Key people:

2

Funding Rounds

$28.7m

Money raised

Predibase is a company developing a low-code AI platform for developers.

Location:

Key people:

4

Funding Rounds

$105.7m

Money raised

SafeGraph is a data company offering a platform for organizing points of interests (POIs) relevant to businesses. It was founded in 2016 and is located in San Francisco, California.

6

Funding Rounds

$80.4m

Money raised

Rasa is a company that offers a conversational AI platform for customized conversations at scale.

4

Funding Rounds

$55.5m

Money raised

Ceres Imaging is a California-based aerial spectral imagery and analytics company that serves farmers and agribusinesses.

Key people:

2

Funding Rounds

$15.5m

Money raised

Moesif is a Caifornia-based company providing API analytics and tools.

4

Funding Rounds

$20.1m

Money raised

Call analytics platform that uses artificial intelligence to transcribe and analyze sales calls, providing enterprises with actionable feedback to improve the performance of their sales teams.

15

Funding Rounds

$249.8m

Money raised

Sift Science is a San Francisco-based company founded in 2011 by Brandon Ballinger.

2

Funding Rounds

$13.6m

Money raised

Determined AI offers an open-source deep learning platform for building algorithmic models.

2

Funding Rounds

$20.3m

Money raised

Chroma is a company developing an open-source embedding database (or vector database) for developing LLM apps.

12

Funding Rounds

$296.1m

Money raised

BigID is a cybersecurity company developing a platform for data protection and privacy compliance.

Key people:

4

Funding Rounds

$18.5m

Money raised

Agent IQ is a company that offers a personal digital platform powered by AI to enhance communication and engagement between banks, credit unions, and their customers.

Key people:

4

Funding Rounds

$743.2m

Money raised

A bioinformatics company in San Francisco building data collection methods and databases that will enable machine learning algorithms in healthcare. It was founded in 2018.

11

Funding Rounds

$29.6m

Money raised

A company that provides a data platform for buildings and properties.

Location:

Key people:

5

Funding Rounds

$249.5m

Money raised

Viz.ai is a healthcare startup that uses artificial intelligence to identify early signs of stroke.

7

Funding Rounds

$249.0m

Money raised

Eko Health is a digital health and AI technology company developing tools for heart and lung disease detection.

Key people:

5

Funding Rounds

$177.0m

Money raised

Capella Space is building a commercial radar satellite constellation. Its headquarters are located in San Francisco, California and it was founded in 2011.

Key people:

7

Funding Rounds

$128.9m

Money raised

Dredrone is an airspace security platform that detects, classifies, and mitigates drone threats.

4

Funding Rounds

$45.0m

Money raised

Company providing service to identify and classify textual content with Artificial Intelligence

3

Funding Rounds

$52.0m

Money raised

3T Biosciences is a biotechnology company developing immunotherapies.

6

Funding Rounds

$96.3m

Money raised

An artificial intelligence company developing deep reinforcement learning technology products for industrial automation.

Industries:

Location:

Key people:

5

Funding Rounds

$200.0m

Money raised

People.ai is an AI platform based on sales and marketing.

1

Funding Rounds

$1.6m

Money raised

Flike is building machine learning (ML)-powered recommender APIs to help engineers personalize discovery pages, feeds, recommended content, customer communication, and more.

Location:

Key people:

4

Funding Rounds

$50.2m

Money raised

Replicate is a company developing a platform for running machine learning models in the cloud.

11

Funding Rounds

$142.5m

Money raised

DroneDeploy is a cloud-based software that allows drones to take images and 3D models at any altitude.

Key people:

4

Funding Rounds

$108.0m

Money raised

An artificial intelligence company with a cognitive process mining software platform that leverages computer vision and machine intelligence for process mining and discovery. It was founded in 2018 and is located San Francisco, California.

1

Funding Rounds

$3.0m

Money raised

Youper is an AI-based emotional health assistant company founded in 2016 by Jose Hamilton Vargas, Diego Dotta and Thiago Antonio Marafon.

4

Funding Rounds

$3.3m

Money raised

An enterprise software company developing computer aided design (CAD) tools for designing and testing DNA sequences.

Location:

Key people:

6

Funding Rounds

$9.1m

Money raised

PRENAV is a company that is digitizing critical infrastructure in the world using AI.

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