69 Best Enterprise Software Startups in San Francisco to Watch in 2025

The Definitive Seedtable Ranking of Enterprise Software Startups in San Francisco

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 349 start-ups with an aggregate funding of $13.8b. The average funding per company in this subset is $200.7m.

Last update to the database: Sep 23, 2025. See changelog.

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9

Funding Rounds

$570.0m

Money raised

Dialpad is a San Francisco-headquartered business communications platform company.

4

Funding Rounds

$583.6m

Money raised

TriNet Zenefits is a software as a service (SaaS) company providing a digital human resources platform for small- and medium-sized enterprises (SMEs).

5

Funding Rounds

$349.2m

Money raised

HashiCorp is a software company providing tools for developers and security professionals to provision, secure, and run infrastructure for distributed applications for organizations.

Key people:

5

Funding Rounds

$121.0m

Money raised

A company offering an email client designed to be the fastest email experience. The company was founded by Conrad Irwin, Rahul Vohra, and Vivek Sodera in 2015 and is headquartered in San Francisco, California.

Location:

Key people:

6

Funding Rounds

$203.6m

Money raised

Loom is a software company that develops communication software for asynchronous presentations through sharable video recordings.

4

Funding Rounds

$108.0m

Money raised

PlanetScale is a database-as-a-service platform acting as a middleware system for MySQL.

Location:

Key people:

8

Funding Rounds

$180.7m

Money raised

Bugcrowd is an enterprise cloud computing and computer security crowdsourcing company that offers a platform for security testing, web, mobile, source code, and client-side applications.

2

Funding Rounds

$15.3m

Money raised

Alloy is a San Francisco-based software company developing a platform for inventory and shipment visibility, including sell-in and sell-through analytics.

5

Funding Rounds

$90.0m

Money raised

Strapi is a company offering an open-source headless content management system (CMS).

4

Funding Rounds

$92.0m

Money raised

Forethought is a San Francisco-based company providing customer service automation using generative AI technology.

Key people:

8

Funding Rounds

$890.1m

Money raised

Lyra helps companies improve access to effective, high-quality mental health care for their employees.

7

Funding Rounds

$120.0m

Money raised

Lever is an Applicant Tracking System which recruiters and hiring managers can use to track their candidates. The company participated in the S12 cohort of Y Combinator.

Location:

Key people:

4

Funding Rounds

$12.2m

Money raised

RethinkDB provides an open-source distributed NoSQL document-oriented database storing JSON documents and scaling data for applications.

3

Funding Rounds

$113.0m

Money raised

Zilliz is a vector database company providing products for enterprise-grade AI.

7

Funding Rounds

$248.0m

Money raised

Sourcegraph offers universal code search for developers and enterprises.

Location:

Key people:

9

Funding Rounds

$434.1m

Money raised

SingleStore is a San Francisco-based database software and analytics company offering a platform to help companies operationalize their data.

Location:

Key people:

6

Funding Rounds

$214.0m

Money raised

Observe.AI is the creator of an AI platform for call centers.

4

Funding Rounds

$159.0m

Money raised

Aera Technology is a software company offering business automation functions.

6

Funding Rounds

$1.1b

Money raised

Rippling is a software company providing cloud-based employee management solutions. It combines human resources, information technology, and operations. It was founded in 2016 and has locations in San Francisco, California and Bangalore, India.

4

Funding Rounds

$188.9m

Money raised

Labelbox is a training data platform with labeling tools, human workforce, data management, API, and automation features for computer vision.

8

Funding Rounds

$362.8m

Money raised

Docker provides an open-source project for deploying applications inside software containers.

4

Funding Rounds

$70.8m

Money raised

A mobile application allowing its users access their office, building or apartment

5

Funding Rounds

$162.5m

Money raised

A company offering a communications platform allows developers to quickly build features that connect to every email, calendar, and contacts provider in the world.

2

Funding Rounds

$8.5m

Money raised

LlamaIndex is an open-source data framework for connecting custom datasets with large language models (LLMs) in order to build applications.

Location:

Key people:

5

Funding Rounds

$48.1m

Money raised

Spire is a company developing tags that provide health tracking including respiration, sleep, stress, activity, and pulse rate.

Location:

Key people:

8

Funding Rounds

$963.0m

Money raised

Bolt is a technology company that has developed a shopping checkout platform for e-commerce.

7

Funding Rounds

$281.3m

Money raised

MindTickle is a company that has developed software tools for business sales

5

Funding Rounds

$141.0m

Money raised

Founded in 2017 by David Hsu, Retool is an internal tool-building company for creating new business applications.

6

Funding Rounds

$94.2m

Money raised

A business intelligence company offering an artificially intelligent analytics web-based software platform .

5

Funding Rounds

$120.7m

Money raised

Hive is an artificial intelligence software company specializing in deep learning and computer vision.

Location:

Key people:

3

Funding Rounds

$107.0m

Money raised

Drift is a software company offering a conversational marketing platform founded in 2015 by David Cancel.

6

Funding Rounds

$693.8m

Money raised

Workrise is a workforce management solution for skilled trades.

Key people:

5

Funding Rounds

$236.0m

Money raised

Monte Carlo is a San Francisco-based software and data company developing a digital data reliability platform for monitoring and alerting users around missing or inaccurate data.

Location:

Key people:

5

Funding Rounds

$73.9m

Money raised

A technology company offering cloud-based device management software for Apple devices.

10

Funding Rounds

$356.8m

Money raised

An automated assistant platform that manages legal paperwork for businesses, founded by Cai GoGwilt and Jason Boehmig.

Key people:

10

Funding Rounds

$36.3m

Money raised

Chronicled is a blockchain company founded by Ryan Orr, Samantha Radocchia, Maurizio Greco and David Aho.

3

Funding Rounds

$36.7m

Money raised

Weaveworks is a company developing a delivery pipeline platform for building and operating applications, helping developers connect, monitor, and manage microservices and containers.

10

Funding Rounds

$116.3m

Money raised

Airware is a San Francisco-based company founded in 2011 by Jonathan Downey.

Location:

Key people:

15

Funding Rounds

$249.8m

Money raised

Sift Science is a San Francisco-based company founded in 2011 by Brandon Ballinger.

5

Funding Rounds

$261.3m

Money raised

Tech company solving bookkeeping for startups and small businesses

Location:

Key people:

3

Funding Rounds

$169.0m

Money raised

A company offering an enterprise workplace visitor management software platform.

4

Funding Rounds

$45.0m

Money raised

Company providing service to identify and classify textual content with Artificial Intelligence

1

Funding Rounds

$1.1m

Money raised

PlanGrid is a company providing a cloud-based construction document collaboration platform. It allows contractors and architects to share from their mobile devices and desktops project plans, markups, photos, specifications and reports. It participated in the W12 cohort of Y Combinator.

9

Funding Rounds

$282.3m

Money raised

Lookout is a cybersecurity company using predictive machine intelligence to analyze data to predict and stop mobile attacks to an individual or an enterprise.

Key people:

5

Funding Rounds

$200.0m

Money raised

People.ai is an AI platform based on sales and marketing.

2

Funding Rounds

$40.5m

Money raised

An insurance technology company offering cloud-based enterprise software for underwriting and quoting employee benefits.

4

Funding Rounds

$3.3m

Money raised

An enterprise software company developing computer aided design (CAD) tools for designing and testing DNA sequences.

Location:

Key people:

7

Funding Rounds

$99.4m

Money raised

Lob is a company developing and building APIs for automating mail and customer communications with print media. It participated in the S13 cohort of Y Combinator.

Location:

Key people:

7

Funding Rounds

$74.0m

Money raised

HappyCo is a company founded in 2011 by Jindou Lee.

2

Funding Rounds

$39.1m

Money raised

Brightside is an employee benefits and financial wellness platform headquartered in San Francisco, California.

Key people:

3

Funding Rounds

$10.9m

Money raised

500Friends was a company developing loyalty marketing programs for brands and retailers. The company was acquired by Merkle in 2014.

7

Funding Rounds

$610.0m

Money raised

Newfront Insurance is a company that provides technologies that are designed to simplify brokerage processes

Key people:

5

Funding Rounds

$75.4m

Money raised

A technology company specializing in creating enterprise software. It was founded in 2013 and is located in San Francisco, California.

Key people:

3

Funding Rounds

$106.0m

Money raised

Workstream is a company and job platform that enables business owners to recruit and hire workers, focusing on gig jobs and the fast food industry.

Location:

Key people:

2

Funding Rounds

$22.1m

Money raised

Codility is a company that looks to develop recruitment software

6

Funding Rounds

$138.7m

Money raised

Pipefy is a software company offering a workflow management and process improvement platform.

Location:

Key people:

7

Funding Rounds

$342.2m

Money raised

Iterable is a company founded in 2013 by Andrew Boni.

Key people:

6

Funding Rounds

$76.0m

Money raised

Simbe Robotics builds automation solutions for shelf auditing and analytics.

Key people:

3

Funding Rounds

$8.0m

Money raised

Bunker is a San Francisco-based small business insurtech company founded by Chad Nitschke.

2

Funding Rounds

$10.3m

Money raised

PullRequest is a company offering code review as a service founded in 2017 by Lyal Avery, Tyler Mann and Patrick Barsallo.

Key people:

8

Funding Rounds

$224.3m

Money raised

Trifacta is a company offering a data wrangling platform.

4

Funding Rounds

$146.0m

Money raised

Rescale is a company developing and providing software platform and hardware infrastructure for companies to perform scientific and engineering simulation.

2

Funding Rounds

$61.0m

Money raised

Gainsight is a privately held service as a software company founded in 2009 by Jim Eberlin and Sreedhar Peddineni. It is headquartered in San Francisco, California.

8

Funding Rounds

$293.8m

Money raised

A company providing an API allowing its users to encode, host and stream videos.

6

Funding Rounds

$144.7m

Money raised

Taulia is a company which provides working capital management and electronic invoicing services for supply chain companies.

3

Funding Rounds

$344.3m

Money raised

Talkdesk is a software company that provides cloud-based call center software solution for enterprises.

1

Funding Rounds

$500.0k

Money raised

Acrossio is a knowledge management company founded in 2012 by Harry Thomos.

4

Funding Rounds

$16.5m

Money raised

Multis is a company that has created a cryptocurrency bank for companies. It was founded in 2018 and is located in San Francisco, California.

1

Funding Rounds

$1.0m

Money raised

Meldium is a software company providing a dashboard that connects and manages accounts and passwords for cloud apps for teams and companies.

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