69 Best Decentralized Finance Startups in United States to Watch in 2025

The Definitive Seedtable Ranking of Decentralized Finance Startups in United States

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 72 start-ups with an aggregate funding of $512.1m. The average funding per company in this subset is $7.4m.

Last update to the database: Feb 18, 2025. See changelog.

See all results for this search

Track over 71,000 companies

Discover
Fast-growing Global startups

Seedtable uses technology and people to track over 71,000 companies to help you find the right ones to partner with.

Pricing + Sign up

3

Funding Rounds

$17.5m

Money raised

Numerai is a hedge fund with stock market trades determined by crowdsourced artificial intelligence models. The best models receive rewards in the form of a cryptographic token called Numeraire (NMR) on the Ethereum blockchain.

1

Funding Rounds

$5.0m

Money raised

Jupiter Exchange is a swap aggregator on Solana.

2

Funding Rounds

$29.5m

Money raised

Immunefi is a bug bounty security services platform that focuses on bug bounty and security services for Web3 projects.

Key people:

2

Funding Rounds

$24.0m

Money raised

Ondo Finance is an open, permissionless, decentralized investment bank

1

Funding Rounds

$8.5m

Money raised

Zeta Markets is the premier derivatives protocol on Solana.

1

Funding Rounds

$2.4m

Money raised

Cake is an all-in-one decentralized finance (DeFi) platform.

Key people:

1

Funding Rounds

$9.0m

Money raised

Primitive - Crypto derivative products built on the Replicating Market Maker protocol, an oracle-free solution to scalable and efficient on-chain derivatives.

Key people:

1

Funding Rounds

$8.0m

Money raised

Regulated crypto exchange. Built the world's first regulated tokenised assets platform. It aims to revolutionise cryptocurrency investment.

Key people:

1

Funding Rounds

$2.1m

Money raised

Cypher is a decentralized synthetic asset protocol.

1

Funding Rounds

$1.0m

Money raised

Increment is a decentralized money market and liquidity engine on Flow blockchain.

1

Funding Rounds

$3.6m

Money raised

A decentralized capital market powered by a cross-margin cross-collateralization clearing engine protocol.

3

Funding Rounds

OpenZeppelin provides security products to build, automate, and operate decentralized applications.

1

Funding Rounds

$5.3m

Money raised

Aperture Finance is a cross-chain marketplace for investing strategies in the decentralized finance domain.

Key people:

1

Funding Rounds

$5.2m

Money raised

Sense Finance is an adding Dimension to DeFi founded in 2021 by Kenton Prescott.

1

Funding Rounds

$8.0m

Money raised

Trading on Any Asset with up to 10x Buying Power. Capital-Efficient Staking with High Yield.

1

Funding Rounds

$3.8m

Money raised

Decentralized exchange for perpetual futures built on Solana

Location:

Key people:

2

Funding Rounds

$7.9m

Money raised

Teller is an algorithmic credit risk protocol, built to enable the creation of decentralized lending markets that can offer unsecured loans, without the need for collateral.

1

Funding Rounds

$1.2m

Money raised

Advanced Cross-Chain Liquidity Aggregation Protocol and cross-chain NFT sale.

1

Funding Rounds

$3.0m

Money raised

MarginFi is a decentralized portfolio margining on Solana founded in 2021.

1

Funding Rounds

$2.0m

Money raised

IndexZoo is a DeFi ecosystem of tokenized ETFs to protect crypto investors from market downturns and volatility risks.

3

Funding Rounds

$24.0m

Money raised

MetaStreet is a decentralized interest rate protocol.

1

Funding Rounds

$34.0m

Money raised

Aligned is a company founded in 2022 by Sam Cassatt.

3

Funding Rounds

$52.0m

Money raised

Entropy is a decentralized asset custody protocol founded in 2021.

1

Funding Rounds

Retrograde is a supercharging Yields and Governance on Terra.

1

Funding Rounds

$1.3m

Money raised

Send Crypto Instantly and Save up to 100x on Ethereum Fees Cheap. Fast. Secure.

1

Funding Rounds

$5.0m

Money raised

Shade Protocol is an array of connected privacy-preserving DeFi applications built on Secret Network

1

Funding Rounds

$2.8m

Money raised

Algofi is a New York-based decentralized finance company offering a blockchain for users to earn yield on their cryptocurrencies without depositing it in a bank or with a centralized custodian.

1

Funding Rounds

Volmex Finance is a protocol focused on implied volatility derivatives.

2

Funding Rounds

$2.3m

Money raised

Layerswap helps Web3 projects onboard users from CEXes, wallets, and other blockchains.

1

Funding Rounds

$1.5m

Money raised

Dexible is an execution management system for DeFi transactions.

1

Funding Rounds

$4.5m

Money raised

Bridgesplit is a NFT fractionalization and liquidity on Solana founded in 2021 by Luke Truitt.

Key people:

1

Funding Rounds

$2.5m

Money raised

Allows users to earn crypto by contributing to a DAO community

1

Funding Rounds

$7.0m

Money raised

Dharma is a decentralized protocol built for the debt market.

1

Funding Rounds

$2.8m

Money raised

We're building the first natively cross chain prime brokerage. We believe the future is multi-chain, and DeFi needs new financial primitives to increase capital efficiency.

2

Funding Rounds

$9.2m

Money raised

A tax-exempt Community Foundation building decentralized financial infrastructure focused on social impact

1

Funding Rounds

$5.0m

Money raised

Tonic DEX is an orderbook DEX on $NEAR.

1

Funding Rounds

$5.0m

Money raised

Porter enables creditworthy DAOs to obtain fixed-rate financing using their project tokens as collateral

1

Funding Rounds

$18.0m

Money raised

The world's most comprehensive DeFi portfolio analytics platform

3

Funding Rounds

$16.0m

Money raised

Set Labs is a company founded in 2017 by Felix Feng, Alex Soong and Justin K Chen.

2

Funding Rounds

$3.5m

Money raised

Combining Decentralized Finance (DeFi) with homebuilding to improve financing for the construction of more homes. Decentralizes lending and coordinates payment flows with construction logistics.

1

Funding Rounds

Dharma Labs is a blockchain company founded in 2017 by Nadav Hollander.

Key people:

2

Funding Rounds

$3.5m

Money raised

Developer of a blockchain-based financial platform intended to provide decentralized financial products. The company specializes in offering access to profitable financial products, without a bank.

Location:

Key people:

1

Funding Rounds

$8.0m

Money raised

Non-fungible token (NFT) lending platform and liquidity engine

1

Funding Rounds

$3.1m

Money raised

Scaling trust in DeFi as the first verification primitive.

1

Funding Rounds

$7.0m

Money raised

Ansible Labs builds a payments platform for blockchain accounts.

Key people:

1

Funding Rounds

$3.2m

Money raised

Domination Finance is a the world's first DEX for dominance trading founded in 2020.

1

Funding Rounds

$2.0m

Money raised

A website that helps crypto borrowers pay less interest on their loans

1

Funding Rounds

$2.0m

Money raised

DFlow is a protocol For Decentralized Order Flow Markets founded by Nitesh Nath.

1

Funding Rounds

$6.0m

Money raised

Volare Finance is a rewarding platform that provides traders with a hedge on their investments in crypto options thanks to its distinctive and unprecedented features.

1

Funding Rounds

$6.2m

Money raised

FARE is a token that can be minted or burned through FARE probability contracts. Developers can build FARE contracts and users can deploy FARE in those contracts for a chance to instantly mint new FARE or burn their FARE.

Industries:

Location:

1

Funding Rounds

$25.0m

Money raised

The Co:Create protocol provides the foundational infrastructure for decentralized brands of the future. It enables projects to mint NFTs, as well as launch their own DAOs and fungible tokens associated with their collections.

1

Funding Rounds

$1.8m

Money raised

Vendible is building a platform that protects your identity and data in DeFi networks

1

Funding Rounds

$3.0m

Money raised

Cashmere is a safer Wallet,Built for Teams founded in 2021 by Shashank Khanna, Rebecca Lee and Charlotte McGinn.

3

Funding Rounds

$375.0k

Money raised

Daxia is a company that designs and develops Open Source Software For Derivatives Contracts On Ethereum.

2

Funding Rounds

$6.0m

Money raised

Liquid staking and yield aggregation protocol, bridging Web3 And DeFi

1

Funding Rounds

$2.0m

Money raised

Native is a Web3 company developing token exchange infrastructure.

1

Funding Rounds

$7.0m

Money raised

The company offers a decentralized and composable data oracle that is integrated with many blockchain platforms to support Defi contracts and leverage recent breakthroughs in zero-knowledge computation by using verifiable and composable data in decentralized applications.

1

Funding Rounds

$5.0m

Money raised

A high-yield treasury platform with built-in security, compliance, and liquidity

Industries:

Key people:

1

Funding Rounds

$7.5m

Money raised

1

Funding Rounds

$15.0m

Money raised

Mauve is a decentralized exchange that provides the compliance of traditional finance. The platform offers its users TradFi-level compliance guarantees to drastically reduce counterparty risk. Mauve relies on Violet's on-chain compliance infrastructure, which issues privacy-preserving compliance credentials, in addition to leveraging multi-facto...

1

Funding Rounds

$7.8m

Money raised

Burrata’s integration layer will help bridge consumer identity and data from silo-ed Web2 systems into Web3

1

Funding Rounds

$15.8m

Money raised

Proven is building a zero-knowledge proof-based trust layer for crypto service providers. The solution enables crypto exchanges, stablecoins, asset managers and custodians to prove their solvency to customers lenders and regulators on a daily basis. The company has already onboarded leading web3 companies, including Coinlist, Bitso, TrueUSD, and...

1

Funding Rounds

$1.0m

Money raised

Web3Port is an accelerator of Web 3 projects helping startupsbuilding from zero to one and to the next level.

2

Funding Rounds

$10.0m

Money raised

Keep playing and earning with your NFTs even when they're collateralized.

1

Funding Rounds

Cetus is a pioneer DEX and concentrated liquidity protocol built on the Sui and Aptos blockchain.

Industries:

Location:

1

Funding Rounds

$4.0m

Money raised

AI Powered Crypto Accounting & Treasury Software - Automated end to end bookkeeping & accounting for Web3 businesses. Stop wasting human capital on accounting close, revaluations, impairment, mark to market, financial statements, reconciliation. Blockchain financial activity & workflows on autopilot.

Industries:

Location:

1

Funding Rounds

$4.2m

Money raised

Any new chain can use Catalyst to permissionlessly connect liquidity and swap with hubs like Ethereum and Cosmos.

Industries:

Location:

1

Funding Rounds

cmorq is a company founded in 2018 by Hossein Azari.

Sign up to access our full database

Enter your email and get access to 71,000 + technology companies you can partner with.

Join 29000+ founders, operators, and investors.