25 Best Cryptocurrency Protocol Startups to Watch in 2025

The Definitive Seedtable Ranking of Cryptocurrency Protocol Startups

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 25 start-ups with an aggregate funding of $281.6m. The average funding per company in this subset is $11.3m.

Last update to the database: Feb 18, 2025. See changelog.

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3

Funding Rounds

$17.5m

Money raised

Numerai is a hedge fund with stock market trades determined by crowdsourced artificial intelligence models. The best models receive rewards in the form of a cryptographic token called Numeraire (NMR) on the Ethereum blockchain.

1

Funding Rounds

$8.5m

Money raised

Zeta Markets is the premier derivatives protocol on Solana.

2

Funding Rounds

$8.5m

Money raised

Decentralized autonomous organization focused on the democratization and innovation in betting

1

Funding Rounds

$4.0m

Money raised

Tempus is a future yield tokenization and fixed rate protocol founded in 2021 by David Garai.

1

Funding Rounds

$18.0m

Money raised

Superfluid is an asset streaming protocol for DAOs and crypto-native businesses.

1

Funding Rounds

$2.1m

Money raised

Pact aims to bring secure, safe and reliable DeFi to the Algorand ecosystem.

1

Funding Rounds

$3.8m

Money raised

Decentralized exchange for perpetual futures built on Solana

Location:

Key people:

2

Funding Rounds

Borrow and lend cryptos on Torches, a leading lending protocol on the secure, fast and low-cost KuCoin Community Chain (KCC). Lend digital assets to earn passive income. Borrow digital assets using collateral without selling the assets.

2

Funding Rounds

$800.0k

Money raised

Lofty AI is a company that uses AI to identify neighborhood growth.

2

Funding Rounds

$35.0m

Money raised

Thetanuts Finance is a protocol designed to help users access crypto-structured products on multiple decentralized networks.

1

Funding Rounds

$2.8m

Money raised

Algofi is a New York-based decentralized finance company offering a blockchain for users to earn yield on their cryptocurrencies without depositing it in a bank or with a centralized custodian.

1

Funding Rounds

$4.2m

Money raised

Brahma aims to simplify the interaction with DeFi primitives through easy to invest vaults, which leverage composability with multiple protocols to deliver superior risk-adjusted yield to users.Brahma provides an alternative to inflationary returns via liquidity mining and discourages mercenary capital .

1

Funding Rounds

$3.3m

Money raised

Risk Harbor is a risk management marketplace for decentralized finance (DeFi) that utilizes a completely automated, transparent, and impartial invariant detection mechanism to secure liquidity providers and stakers against smart contract risks, hacks, and attacks.

Key people:

2

Funding Rounds

$40.0m

Money raised

Katana is a the yield generation protocol for Solana founded by Ayush Menon.

3

Funding Rounds

$32.3m

Money raised

Balancer Lab's mission is to become the primary source of DeFi liquidity.

2

Funding Rounds

$8.3m

Money raised

ALEX is an open-source DeFi protocol.

1

Funding Rounds

$5.5m

Money raised

Friktion is DeFi's first full-stack portfolio manager - built for DAOs, individuals, and traditional institutions.

1

Funding Rounds

$2.0m

Money raised

Build your own web3 world with your wallet activities. Built on top of @ensdomains.

2

Funding Rounds

$6.0m

Money raised

Liquid staking and yield aggregation protocol, bridging Web3 And DeFi

1

Funding Rounds

$2.0m

Money raised

Native is a Web3 company developing token exchange infrastructure.

2

Funding Rounds

$8.0m

Money raised

Efficient liquidity standard for staking and crowdloan assets on Polkadot

1

Funding Rounds

$3.7m

Money raised

Hedge offers 0% interest loans on Solana in form of our CDP stablecoin $USH with the lowest collateral ratios available on Solana

1

Funding Rounds

$12.0m

Money raised

WOOFi, built by WOO Network, offers the best trade execution and lowest swap fee, opportunities to earn sustainable yields on crypto, and a high-efficiency solution for on-chain liquidity provision.

1

Funding Rounds

$50.0m

Money raised

Energiswap is decentralized trading powered by Energi.

1

Funding Rounds

$3.3m

Money raised

Hubble Exchange is a Multi-collateral/Cross-Margin Perpetual Futures on Avalanche.

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