45 Best B2b Startups in United States to Watch in 2025

The Definitive Seedtable Ranking of B2b Startups in United States

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 45 start-ups with an aggregate funding of $5.0b. The average funding per company in this subset is $112.1m.

Last update to the database: Feb 18, 2025. See changelog.

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4

Funding Rounds

$126.0m

Money raised

Mercury is a company making banking products for startups based in San Francisco and backed by a16z.

Key people:

7

Funding Rounds

$30.3m

Money raised

Mattermark is a San Francisco-based company founded by Kevin Morrill, Danielle Morrill and Andy Sparks.

Key people:

3

Funding Rounds

$305.0m

Money raised

Moveworks is an AI, machine learning, enterprise natural language understanding (NLU) and chatbot platform that resolves IT Service Desk support issues.

4

Funding Rounds

$45.0m

Money raised

Company providing service to identify and classify textual content with Artificial Intelligence

5

Funding Rounds

$200.0m

Money raised

People.ai is an AI platform based on sales and marketing.

9

Funding Rounds

$617.8m

Money raised

Carbon Health is a healthcare company. They primarily serve California and the Reno area.

4

Funding Rounds

$308.0m

Money raised

A San Francisco-based company developing an email security platform for Microsoft Office 365.

3

Funding Rounds

$47.5m

Money raised

Metadata is a company founded by Gil Allouche.

Key people:

5

Funding Rounds

$132.7m

Money raised

Notable Health is an artificial intelligence-powered health start up in California that focuses on automating and digitizing physician-patient interactions.

Key people:

5

Funding Rounds

$80.0m

Money raised

Veem is a San Francisco-based financial technology company creating a platform for business to business payments.

1

Funding Rounds

$10.0m

Money raised

BlueCart is an online ordering platform that connects wholesale suppliers and buyers in the hospitality industry.

5

Funding Rounds

$20.4m

Money raised

Klarity provides an automated contract review solution for enterprises.

7

Funding Rounds

$571.8m

Money raised

DriveWealth partners with global financial institutions, brokers, app developers, and technology companies to give everyone, everywhere the ability to open a US-based brokerage account and invest for their financial futures. Partners of DriveWealth can offer their customers the ability to invest in the US equities market through our robust set of FIX and RESTful APIs or our custom branded product solution.

4

Funding Rounds

$18.9m

Money raised

A company offering a voice first care management platform that is headquartered in Boston, Massachusetts and was founded in 2014 by Dr. Aiden Feng, Emanuele Musini, and James Wyman.

7

Funding Rounds

$115.3m

Money raised

Company

2

Funding Rounds

$4.6m

Money raised

Developer of a B2B mobile platform designed to fill empty salon chairs on demand. The company's platform matches salon and barbershop owners with licensed beauty professionals, enabling stylists to find and book working spaces for rent.

Key people:

1

Funding Rounds

$82.0m

Money raised

Cellares is a biotechnology and cell therapy company founded in 2019 by Fabian Gerlinghaus, Alex Pesch, and Omar Kurdi.

8

Funding Rounds

$278.2m

Money raised

Company

1

Funding Rounds

$6.5m

Money raised

Flip CX is a software company based in New York, NY offering a voice-based AI customer service technology designed to automate customer service phone calls.

Key people:

1

Funding Rounds

$300.0k

Money raised

Prifina is a blockchain company founded in 2018 by Valto Loikkanen, Markus Lampinen and Jouko Ahvenainen.

Industries:

Key people:

2

Funding Rounds

$13.5m

Money raised

Spoiler Alert is a B2B technology company making a software platform for CPG brands to manage sales of excess and short-dated food inventory, recovering value and increasing sustainability.

Location:

Key people:

2

Funding Rounds

$7.0m

Money raised

Court Buddy is a company founded in 2015 by Kristina Jones.

2

Funding Rounds

$840.3k

Money raised

ParLevel Systems is a company founded in 2013 by Walter Teele Vera, Rafael Barroso, Luis P Gonzalez, Alan Munson, Gabriel Senior and Alfonso García.

Key people:

7

Funding Rounds

$257.6m

Money raised

G2 is a company founded by Michael Wheeler.

Key people:

1

Funding Rounds

$1.5b

Money raised

Articulate is a company founded in 2002 by Adam Schwartz.

2

Funding Rounds

$33.0m

Money raised

AiDash is an AI-first vertical SaaS company. AiDash is a SaaS company that enables satellite-powered operations and maintenance for utility, energy, and other core industries.

Key people:

2

Funding Rounds

$70.0m

Money raised

ActivTrak is a company founded in 2009.

1

Funding Rounds

$1.4m

Money raised

Pict is a company founded by Kele Dobrinski.

2

Funding Rounds

$32.0m

Money raised

Sonde Health is a Boston-based digital health company developing voice-based technologies for monitoring and diagnosing mental and physical health.

Location:

Key people:

1

Funding Rounds

$13.0m

Money raised

Social Tables is a company founded in 2011.

2

Funding Rounds

$17.7m

Money raised

Epsilon3 is a Los Angeles, California-based company developing a software platform for spacecraft and operations management.

Key people:

1

Funding Rounds

$1.0m

Money raised

Fooda is a company founded in 2011 by Orazio Buzza.

Key people:

3

Funding Rounds

$24.0m

Money raised

Slope is a San Francisco-based fintech startup that provides a lending platform for businesses.

Key people:

1

Funding Rounds

$1.0m

Money raised

Spinnakr is a United States-based company founded in 2011 by Michael Mayernick.

Industries:

Location:

Key people:

1

Funding Rounds

$120.0k

Money raised

Gilded is a company founded in 2018 by Gil Hildebrand, Ken Gaulter and Raina Casbon-Kelts.

Key people:

2

Funding Rounds

$12.5m

Money raised

AutoFi is a company founded in 2015 by Jonathan Palan, Kevin Singerman and Mandar Gokhale.

Key people:

1

Funding Rounds

$50.0k

Money raised

SYNCFAB is a company founded in 2013 by Andy Tong.

2

Funding Rounds

$800.0k

Money raised

Operator of web3 studio building platform intended for creator payments and content distribution infrastructure. The company's platform specializes in web3 dpps and tokens to build a new economy digitally for art and culture, enabling black and African creators to build sustainable prosperity through community, storytelling and collaboration.

Key people:

1

Funding Rounds

$50.0m

Money raised

Scopio is a company founded in 2019 by Christina Hawatmeh.

1

Funding Rounds

$4.0m

Money raised

ReSec Technologies is a provider of content disarm and reconstruction technology

1

Funding Rounds

$400.0k

Money raised

1

Funding Rounds

$2.0m

Money raised

Kabata is a fitness platform intended to provide workout equipment, gamified progression, and data-driven coaching.

1

Funding Rounds

$3.7m

Money raised

Innovation Department is a company founded in 2014 by Alex Song.

Key people:

1

Funding Rounds

$40.0k

Money raised

atCollab is a company founded in 2012 by Mikhail Kartamyshev.

1

Funding Rounds

$120.0k

Money raised

HotDrop is a United States-based company.

Industries:

Location:

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