69 Best Startups in Lyon to Watch in 2025

The Definitive Seedtable Ranking of Startups in Lyon

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 105 start-ups with an aggregate funding of $1.1b. The average funding per company in this subset is $15.9m.

Last update to the database: Dec 2, 2025. See changelog.

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1

Funding Rounds

$1.2m

Money raised

Exorde is the web3 protocol that empowers developers to scrape and link all public data on the web.

Industries:

Location:

Key people:

8

Funding Rounds

$59.9m

Money raised

MaaT Pharma (Microbiota as a Therapy) is a French biotech start-up, created at the end of 2014, to treat diseases linked to imbalances in the intestinal microbiome.

6

Funding Rounds

$37.4m

Money raised

Developer of vaccines to provide broad-spectrum protection against highly mutating respiratory viruses.

Location:

Key people:

1

Funding Rounds

$1.5m

Money raised

DOZ provides an all-in-one marketing software.

Location:

Key people:

3

Funding Rounds

$6.5m

Money raised

Mojo provides fertility care through partnering tech experts with fertility experts.

Location:

Key people:

3

Funding Rounds

$104.5m

Money raised

Developer of FXR agonists for the treatment of severe kidney diseases.

2

Funding Rounds

$33.8m

Money raised

Battery-free IoT manufacturer powered by ambient indoor light

Location:

Key people:

1

Funding Rounds

Servoy is a company founded in 2001 by Ron van der Burg.

1

Funding Rounds

$3.0m

Money raised

Software platform and professional services for complex systems modeling and simulation, targeting in particular energy networks and urban planning applications.

Location:

Key people:

1

Funding Rounds

$2.3m

Money raised

Koban is a company founded in 2021.

4

Funding Rounds

$9.8m

Money raised

Carbon emissions and life cycle assessments (LCA) platform for construction projects.

2

Funding Rounds

$1.3m

Money raised

MailClark is an artificial Intelligence company founded in 2014 by Anthony BLETON-MARTIN, Antoine Lefeuvre, Julian ESPERAT and Gilles FELIX.

Location:

Key people:

3

Funding Rounds

$36.2m

Money raised

French biotechnology company that usesprecision fermentation to produce real dairy products,accessible to everyone

Location:

1

Funding Rounds

$3.0m

Money raised

Novadiscovery is an in silico Prediction of Drug Efficacy founded in 2010 by Jean-Pierre Boissel, François-Henri Boissel and Frédéric Cogny.

Location:

Key people:

2

Funding Rounds

Lavorel Medicare is a Luxembourg City-based service provider specialized in nursing care at home or in special care units.

2

Funding Rounds

$220.0m

Money raised

Amolyt Pharma is a therapeutic Peptides founded in 2015.

6

Funding Rounds

$21.1m

Money raised

Clim8 develops intelligent thermal technologies for wearables, includung intelligent heated clothing systems.

3

Funding Rounds

$118.6m

Money raised

SaaS platform for SMBs to manage and forecast their cash flows.

4

Funding Rounds

$57.1m

Money raised

Adocia is a molecular Delivery System for Therapeutic Proteins founded in 2005.

2

Funding Rounds

$1.9m

Money raised

Mojo Diagnostics is a healthcare company offering male fertility analysis.

Location:

Key people:

2

Funding Rounds

$24.0m

Money raised

SaaS solution using artificial intelligence for HR recommendations.

Location:

Key people:

2

Funding Rounds

$1.2m

Money raised

Nyctale is a Crypto-Assets Analytics founded in 2018.

5

Funding Rounds

$18.8m

Money raised

Mobile gaming studio.

Industries:

Location:

1

Funding Rounds

$900.6k

Money raised

Platform that turns any digital service into a collaborative experience mimicking real-life human interactions.

Location:

Key people:

1

Funding Rounds

$11.0m

Money raised

Sentryo is a software vendor providing cybersecurity solutions for industrial and IoT networks.

1

Funding Rounds

$2.6m

Money raised

Nosopharm is an anti-infectives, Peptide founded in 2009 by Philippe VILLAIN-GUILLOT.

2

Funding Rounds

$29.5m

Money raised

Brenus Pharma is a cancer vaccine developer founded in 2021 by Benoit Pinteur.

Location:

Key people:

2

Funding Rounds

$15.5m

Money raised

Platform that streamlines and automates vulnerability management in cybersecurity.

1

Funding Rounds

$10.0m

Money raised

Datagalaxy is a collaborative data governance solutions founded in 2015.

1

Funding Rounds

$20.3m

Money raised

Poxel is a biopharmaceutical company developing drugs for metabolic diseases founded in 2009.

3

Funding Rounds

$39.6m

Money raised

Mablink Bioscience is an antibody-drug Conjugates founded in 2018.

1

Funding Rounds

$6.3m

Money raised

Healshape is a 3D bioprinting regenerative medecine company.

Location:

1

Funding Rounds

$1.7m

Money raised

Eden AI is an AI integration platform founded in 2021.

1

Funding Rounds

$19.0m

Money raised

RED Horticulture specializes in horticulture LED lighting systems, photobiology research, and indoor and greenhouse lighting.

1

Funding Rounds

$4.3m

Money raised

Platform offering assistance to patients and their families to enhance abilities, autonomy, and quality of life.

1

Funding Rounds

$11.0m

Money raised

ProovStation is an automated drive-through bay which detects and analyses vehicle damages.

$1.7m

Money raised

Mon Petit Placemen is a digital investment platform founded in 2017.

1

Funding Rounds

$3.6m

Money raised

Sopht is the first GreenOps platform to decarbonize corporate IT.

1

Funding Rounds

$960.0k

Money raised

Time and budget AI bot that help teams to work together

1

Funding Rounds

$7.1m

Money raised

Educational hub specializing in revealing talent and developing skills through three higher education schools focused on the video game industry.

Location:

1

Funding Rounds

$14.0m

Money raised

Platform that monitors company solvency by providing legal information.

1

Funding Rounds

$9.0m

Money raised

Access visual health directly where you live and work !

2

Funding Rounds

$1.2m

Money raised

Adrenalead is a web push notification advertising platform founded in 2018 by Edouard Ducray.

Location:

Key people:

1

Funding Rounds

$3.8m

Money raised

Platform for improving procurement team performance through agile management.

$5.7m

Money raised

Their policy is geared towards quality and customer satisfaction

Location:

1

Funding Rounds

$3.4m

Money raised

LabLabee is a hands-on training platform for telco cloud providers founded in 2021 by Samir Tahraoui.

2

Funding Rounds

$3.2m

Money raised

Agency specializing in custom Python web application development.

1

Funding Rounds

$2.8m

Money raised

AugmentedCISO is a cybersecurity SaaS dedicated to CISO founded in 2021.

1

Funding Rounds

$9.9m

Money raised

Advanced Biodesign is a contract Research & Development founded in 2010.

1

Funding Rounds

$6.0m

Money raised

Diagnoly is an AI-powered solutions provider for medical imaging founded in 2020 by Edwin Quarello.

Location:

Key people:

1

Funding Rounds

$30.0k

Money raised

AGRIFIND is a web-based agricultural platform for farmers founded in 2016.

1

Funding Rounds

$670.0k

Money raised

Solution enhancing human perception, initially for visually impaired individuals.

1

Funding Rounds

$20.4m

Money raised

Varioptic is a company founded in 2002.

Location:

1

Funding Rounds

$930.0k

Money raised

Cloud-based Clinical Data Management System for decentralized clinical trials.

1

Funding Rounds

$1.2m

Money raised

Digital platform providing essential information for medical and healthcare professionals.

Location:

1

Funding Rounds

$727.3k

Money raised

Alinto is an email management platform founded in 2000.

Location:

1

Funding Rounds

$2.3m

Money raised

Rutile.bike is an online marketplace for refurbished electric bikes founded in 2021 by Thibaud Thome.

Location:

Key people:

1

Funding Rounds

$660.0k

Money raised

Smash is a platform for internet-based IT and communication services.

1

Funding Rounds

$21.0m

Money raised

Axoltis Pharma is a therapeutic solutions developer for neurodegenerative diseases founded in 2003.

1

Funding Rounds

$4.6m

Money raised

Fungu'it is a provider of natural fermented aromatic solutions founded in 2022 by Anas Erridaoui.

Location:

Key people:

1

Funding Rounds

$880.0k

Money raised

Platform that lets users create websites and centralize all their online content for easy sharing with their community.

2

Funding Rounds

$20.7m

Money raised

GEOLID is a search optimization platform focused on French consumers founded in 2008.

Industries:

Location:

1

Funding Rounds

$2.6m

Money raised

Miraxess is a smartphone-powered laptops founded in 2015.

Location:

1

Funding Rounds

$730.0k

Money raised

Mon Bel Appart is a French real estate company that provides property management and consultancy services.

1

Funding Rounds

$860.0k

Money raised

3D scanning service providing product size recommendations and tailor-made items.

1

Funding Rounds

$1.1m

Money raised

SaaS solution for textile and promotional items that simplifies the production and management of graphic operations.

1

Funding Rounds

$3.5m

Money raised

Developer of immunotherapies for the treatment of cancer

Location:

Key people:

1

Funding Rounds

$2.2m

Money raised

Previa Medical is an AI to detect patients complication risks founded in 2020.

1

Funding Rounds

$1.6m

Money raised

Platform offering security, digital tools, confidentiality, regulatory compliance, KYC, and collaboration services for businesses and banks.

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