69 Best Smart Contract Startups in United States to Watch in 2026

The Definitive Seedtable Ranking of Smart Contract Startups in United States

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 72 start-ups with an aggregate funding of $5.7b. The average funding per company in this subset is $83.0m.

Last update to the database: Mar 31, 2026. See changelog.

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4

Funding Rounds

$910.0m

Money raised

An end-to-end blockchain and NFT solution for video games.

3

Funding Rounds

$17.5m

Money raised

Numerai is a hedge fund with stock market trades determined by crowdsourced artificial intelligence models. The best models receive rewards in the form of a cryptographic token called Numeraire (NMR) on the Ethereum blockchain.

3

Funding Rounds

$119.2m

Money raised

Phantom is a cryptocurrency wallet by Solana to manage digital assets and access decentralized applications.

1

Funding Rounds

$5.0m

Money raised

Jupiter Exchange is a swap aggregator on Solana.

7

Funding Rounds

$165.1m

Money raised

Figment is a blockchain infrastructure and software provider.

Location:

Key people:

3

Funding Rounds

$54.2m

Money raised

Layer1 is a cryptocurrency investment and infrastructure platform.

2

Funding Rounds

$24.0m

Money raised

Ondo Finance is an open, permissionless, decentralized investment bank

3

Funding Rounds

$764.7m

Money raised

Bitmain is a Beijing-based multinational semiconductor company, founded in 2013, that manufactures products for blockchain and artificial intelligence (AI) applications.

3

Funding Rounds

$2.3m

Money raised

A web and API platform that provides Bitcoin and Altcoin conversion.

1

Funding Rounds

$8.5m

Money raised

Zeta Markets is the premier derivatives protocol on Solana.

1

Funding Rounds

$6.0m

Money raised

Maximum protection and yield, fully protected through Protocol Controlled Underwriting.

1

Funding Rounds

$2.4m

Money raised

Cake is an all-in-one decentralized finance (DeFi) platform.

Key people:

6

Funding Rounds

$898.4m

Money raised

Wise, previously TransferWise, is a company that offers money transfers services founded by Kristo Käärmann and Taavet Hinrikus.

3

Funding Rounds

$15.4m

Money raised

SynFutures is a decentralized Derivatives Protocol.

1

Funding Rounds

$9.0m

Money raised

Primitive - Crypto derivative products built on the Replicating Market Maker protocol, an oracle-free solution to scalable and efficient on-chain derivatives.

Key people:

1

Funding Rounds

$8.0m

Money raised

Regulated crypto exchange. Built the world's first regulated tokenised assets platform. It aims to revolutionise cryptocurrency investment.

Key people:

22

Funding Rounds

$1.4b

Money raised

BlockFi is a blockchain platform for high-interest crypto accounts and low-cost credit products.

Key people:

5

Funding Rounds

$75.9m

Money raised

Unstoppable Domains is a company that offers alt-route domain names based on blockchain technology.

2

Funding Rounds

$15.2m

Money raised

Lit Protocol is decentralized access control designed to bring more utility to the web.

6

Funding Rounds

$9.8m

Money raised

Facial recognition company Kairos today announced the alpha release of the Kairos Protocol, a biometric verification system for cryptocurrency transactions.

3

Funding Rounds

$8.6m

Money raised

Nebula Genomics is a genetics company developing a platform for individuals to get their personal genome sequenced, and then enable them to store and control that information through cryptographic encryption on the blockchain.

Key people:

2

Funding Rounds

$157.0m

Money raised

Magic Eden is a California-based company that has developed a multi-chain non-fungible token (NFT) platform of the same name.

1

Funding Rounds

$170.0m

Money raised

Autograph is an NFT platform that brings together the iconic brands in sports and culture to create unique digital collections.

1

Funding Rounds

$5.2m

Money raised

Sense Finance is an adding Dimension to DeFi founded in 2021 by Kenton Prescott.

1

Funding Rounds

$8.0m

Money raised

Trading on Any Asset with up to 10x Buying Power. Capital-Efficient Staking with High Yield.

1

Funding Rounds

$3.8m

Money raised

Decentralized exchange for perpetual futures built on Solana

Location:

Key people:

1

Funding Rounds

$1.2m

Money raised

Advanced Cross-Chain Liquidity Aggregation Protocol and cross-chain NFT sale.

3

Funding Rounds

$82.5m

Money raised

Lightning Labs is a software development company based in San Francisco developing software for the Lightning Network.

Key people:

1

Funding Rounds

$8.5m

Money raised

Heavy Rain is a video game founded in 2018 by Manoj Duggirala.

1

Funding Rounds

$200.0k

Money raised

Alkemi is a blockchain company founded in 2018 by Ryan Breen.

1

Funding Rounds

$1.3m

Money raised

Send Crypto Instantly and Save up to 100x on Ethereum Fees Cheap. Fast. Secure.

5

Funding Rounds

$58.0m

Money raised

Platform that allows developers to build web3 applications

Key people:

2

Funding Rounds

$5.0m

Money raised

BTCC is a company offering a platform for exchanging cryptocurrencies and holding digital currencies in cryptocurrency wallets.

Key people:

1

Funding Rounds

$2.5m

Money raised

Allows users to earn crypto by contributing to a DAO community

1

Funding Rounds

$6.0m

Money raised

Linera is a new blockchain protocol with low-latency applications founded in 2021 by Mathieu Baudet.

Location:

Key people:

2

Funding Rounds

$9.6m

Money raised

Battlebound is a where world-class gameplay meets play-to-earn.

2

Funding Rounds

$4.0m

Money raised

RockX provides products for stakeholders.

Key people:

4

Funding Rounds

$25.5m

Money raised

Merkle Science provides blockchain monitoring solutions to help detect and prevent illegal activi...

Key people:

3

Funding Rounds

$67.7m

Money raised

Azra Games is a blockchain-based developer of collectible and combat games.

Key people:

4

Funding Rounds

$57.0m

Money raised

Simba Chain is a cloud-based SCaaS platform that enables users to implement decentralized applications dapps for blockchain.

1

Funding Rounds

$7.0m

Money raised

Dharma is a decentralized protocol built for the debt market.

1

Funding Rounds

$1.2m

Money raised

Hatchfi is a developer API for connecting your users' crypto wallets and accounts to your application with just a few lines of code.

3

Funding Rounds

$11.3m

Money raised

Developer of non-fungible token calculator platform intended to analyze, track and discover NFTs. The company's platform allows users to buy, sell and analyze digital collectibles, enabling users to make it easy to understand decisions around buying and selling NFTs.

Key people:

3

Funding Rounds

$1.7m

Money raised

Distributed Systems is a San Francisco-based company founded in 2015 by Franz Alexander Kern, Nikhil Srinivasan and Alexander Kern.

Key people:

1

Funding Rounds

$400.0m

Money raised

Paradigm is a company founded in 2018 by Anand Gomes, Sharaf Nassar and michal koonin.

Key people:

1

Funding Rounds

$20.0m

Money raised

OpenNode is a company founded in 2018 by afnan rahman, brandon lewis and joao almeida.

1

Funding Rounds

$1.5m

Money raised

Geopay.me, Inc., is a privately held US money service business and alternative payment network registered with the US Treasury and FINCEN. The company is focused on easing consumer and merchant adoption of digital currencies.

Key people:

1

Funding Rounds

$3.6m

Money raised

IBC based multi-cluster routing/roll-up protocol providing E2E IBC connectivity across ecosystems

2

Funding Rounds

$14.0m

Money raised

Trustcheck is a free scam prevention tool for those transacting withcryptocurrencies, smart contracts and non-fungible tokens developed by Web3 Builders.

Key people:

3

Funding Rounds

$6.2m

Money raised

MetaOne is a the ONE Platform for guilds and gamers founded in 2020 by Marrtin Hoon.

Location:

Key people:

2

Funding Rounds

$3.5m

Money raised

Combining Decentralized Finance (DeFi) with homebuilding to improve financing for the construction of more homes. Decentralizes lending and coordinates payment flows with construction logistics.

1

Funding Rounds

$3.0m

Money raised

Dirt Protocol is an openly editable datastore on Ethereum founded in 2018.

1

Funding Rounds

$1.3m

Money raised

Sagewise is a new start up that serves as a safety net for smart contracts and resolve disputes using blockchains and cryptocurrency.

1

Funding Rounds

$3.5m

Money raised

SKNUPS is a metaverse platform open to everyone where you can discover and own the latest digital fashion collectibles – SKNs

Location:

Key people:

1

Funding Rounds

$25.0m

Money raised

The Co:Create protocol provides the foundational infrastructure for decentralized brands of the future. It enables projects to mint NFTs, as well as launch their own DAOs and fungible tokens associated with their collections.

2

Funding Rounds

$5.1m

Money raised

Amber Labs is a company founded in 2017.

2

Funding Rounds

$3.3m

Money raised

The first financial markets for open game economies

2

Funding Rounds

$375.0k

Money raised

Quidli is a company founded in 2018 by Guillaume Figielski.

1

Funding Rounds

$2.0m

Money raised

Native is a Web3 company developing token exchange infrastructure.

1

Funding Rounds

$100.0k

Money raised

Epazz is a company making enterprise blockchain cloud-based software solutions founded in 2000 by Shaun Passley.

1

Funding Rounds

$300.0k

Money raised

Blockchain company

1

Funding Rounds

$5.0m

Money raised

Rootdata is a visual and structured crypto projects data provider, offering crypto investors and entrepreneurs with fundraising data with more transaction clues, and is committed to becoming a data entry for discovering high-quality crypto assets.

1

Funding Rounds

$21.0m

Money raised

We build games for 5B football fans, featuring your favorite players. Official partner of FIFA and FIFPRO.

Location:

Key people:

1

Funding Rounds

$3.7m

Money raised

Hedge offers 0% interest loans on Solana in form of our CDP stablecoin $USH with the lowest collateral ratios available on Solana

1

Funding Rounds

$3.0m

Money raised

The smart contract wallet backed by the Ethereum community.

Location:

Key people:

1

Funding Rounds

$2.5m

Money raised

Diagonal is a platform aiming to make it easier for Web 3 companies to process subscriptions.

Key people:

1

Funding Rounds

$3.6m

Money raised

The Kingdom is an upcoming open world metaverse focusing on culture-led experiences

1

Funding Rounds

SoHo Token Labs is a company founded in 2018.

1

Funding Rounds

$18.0m

Money raised

Omni is an infrastructure layer for Ethereum that empowers developers to build applications across all rollups without fragmenting liquidity

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