69 Best Health Tech Startups in San Francisco to Watch in 2025

The Definitive Seedtable Ranking of Health Tech Startups in San Francisco

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 561 start-ups with an aggregate funding of $19.1b. The average funding per company in this subset is $276.6m.

Last update to the database: Feb 18, 2025. See changelog.

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3

Funding Rounds

$364.2m

Money raised

Neuralink is a company that develops brain-computer interface (BCI) devices to assist people with paralysis and blindness and technologies that may expand the abilities of humans.

Location:

Key people:

5

Funding Rounds

$263.1m

Money raised

Mammoth Biosciences is an American company based in San Francisco founded on June 1, 2017. Mammoth Biosciences uses CRISPR technology to develop bio-sensing technologies for diagnostics in industries such as healthcare, agriculture, manufacturing, and forensics and genome editing therapeutics.

1

Funding Rounds

$50.0k

Money raised

Pembient uses advances in biotechnology to fabricate horn and other wildlife products to combat the threat to endangered species.

5

Funding Rounds

$5.1m

Money raised

Indee Labs focuses on the development of microfluidic vortex shedding for rapidly and efficiently transfecting human primary immune cells with negligible perturbation. The team is focused on developing its core technology for short turnaround chimeric antigen receptor T cell (CAR-T) development and manufacturing.

Location:

Key people:

10

Funding Rounds

$1.3b

Money raised

Brex is a credit card company that issues corporate credit cards with no security deposit.

Location:

Key people:

7

Funding Rounds

$711.5m

Money raised

Perfect Day Foods (formerly Muufri) engineered yeast capable of producing the proteins found in cows milk. They use these proteins to make their own line of animal-free dairy products.

Key people:

9

Funding Rounds

$20.3m

Money raised

New Wave Foods is a biotechnology company developing plant-based shellfish food products. The company is based out of San Francisco, California and was founded in 2015 by Dominique Barnes and Michelle Wolf.

8

Funding Rounds

$220.0m

Money raised

Just, Inc. (formerly known as Hampton Creek) is a food technology company developing and selling plant based food products around the world.

Location:

Key people:

5

Funding Rounds

$115.9m

Money raised

Nurx is a telemedicine service company that delivers oral contraceptives and various testing kits to its customers. It was founded in 2015 and has headquarters in San Francisco, California.

8

Funding Rounds

$551.0m

Money raised

Eat Just is a San Francisco based food technology company founded in 2011. The company is known for its bean-based egg substitute called Just Egg. Eat Just also produces egg-free mayonnaise.

4

Funding Rounds

$580.8m

Money raised

Upside Foods is a San Francisco-based company making cultured meat products. The company was founded by Uma Valeti, Nicholas Genovese, and Will Clem.

4

Funding Rounds

$1.8b

Money raised

Grail is a biotechnology company headquartered in Menlo Park, California that was founded as a spinoff of Illumina Inc and initially headed by Jeffrey Huber in 2016, focused on making a medical device that can detect early stage cancer.

11

Funding Rounds

$4.1b

Money raised

The World's First Digital Clinic for Back and Joint Pain

Location:

Key people:

1

Funding Rounds

Stämm is downsizing a whole biotech facility into an all-in-one, pug-n-play desktop unit called The Bioprocessor.

2

Funding Rounds

$3.4m

Money raised

Chai Biotechnologies (also known as Chai and Chai Bio) is a biotechnology company building real-time PCR, qPCR and devices that detect pathogens, speciate meat and genotype DNA.

3

Funding Rounds

$125.0m

Money raised

Synchron, Inc. is a technology company building implantable neural interface solutions, including endovascular brain-computer interface.

8

Funding Rounds

$71.3m

Money raised

Notable Labs is a company providing personalized drug combination testing service for cancer patients.

9

Funding Rounds

$276.0m

Money raised

A diagnostic DNA testing company using quantified biological data.

3

Funding Rounds

$14.3m

Money raised

Aria Pharmaceuticals is a first-in-class pharmaceutical discovery and development founded in 2014 by Andrew M. Radin.

2

Funding Rounds

$158.0m

Money raised

Senti Biosciences is a synthetic biology company.

4

Funding Rounds

$160.0m

Money raised

Suki is a Redwood City, California-based technology company developing AI-powered administrative tools for the healthcare industry.

3

Funding Rounds

$313.0m

Money raised

Flatiron Health is a startup that organizes real-time oncology data to help cancer patients and doctors.

11

Funding Rounds

$50.0m

Money raised

An industrial biotech company developing a commercial bioprocess for manufacturing bio-based malonic acid.

2

Funding Rounds

$120.0m

Money raised

Scribe Therapeutics develops molecular engineering solutions for CRISPR-based genetic medicine.

6

Funding Rounds

$88.0m

Money raised

Prellis Biologics is developing technology to build transplantable human organs and tissues.

Location:

Key people:

6

Funding Rounds

$714.0m

Money raised

An insurance technology offering a platform for companies to manage health insurance policies for their employees.

5

Funding Rounds

$48.1m

Money raised

Spire is a company developing tags that provide health tracking including respiration, sleep, stress, activity, and pulse rate.

Location:

Key people:

7

Funding Rounds

$21.2m

Money raised

Wild Earth is a biotechnology company using cellular agriculture to produce high-protein pet food.

8

Funding Rounds

$132.0m

Money raised

Practice Fusion is a San Francisco-based developer of electronic health record and medical practice management software.

9

Funding Rounds

$411.9m

Money raised

Benchling is a company based in San Francisco focusing on life science collaboration, both private and public, through creating cloud based software tools for digital DNA sequence editing, designing and running experiments, analyzing data, and sharing research.

Industries:

Location:

Key people:

6

Funding Rounds

$4.6m

Money raised

Nanomedicine company developing vaccines and therapies with cell-specific targeting.

8

Funding Rounds

$459.7m

Money raised

Silicon Valley-based genetic engineering startup.

Key people:

2

Funding Rounds

$22.8m

Money raised

Emerald Therapeutics is a biotechnology company located in San Fransisco, California, founded by Brian Frezza and DJ Klienbaum in 2010. Emerald Therapeutics offers cloud a based software and hardware platform that allows researchers to remotely perform automated scientific laboratory experiments.

10

Funding Rounds

$36.3m

Money raised

Chronicled is a blockchain company founded by Ryan Orr, Samantha Radocchia, Maurizio Greco and David Aho.

4

Funding Rounds

$84.5m

Money raised

SCiFi Foods (formerly Artemys Foods) is a company that makes and provides meat that is animal-free

4

Funding Rounds

$140.0m

Money raised

Mission Bio is a South San Francisco based company that develops single-cell DNA analysis and precision genomics.

6

Funding Rounds

$46.0m

Money raised

A company using RNA to diagnose disease and to develop biomarkers that predict treatment outcomes. Cofactor is founded by Jarret Glasscock.

Key people:

3

Funding Rounds

$350.0k

Money raised

A biotechnology company that is building a smart toilet monitor for non-invasive early detection of gastrointestinal cancers and diseases. It was founded in 2016 and is located in San Francisco, California.

3

Funding Rounds

$8.6m

Money raised

Nebula Genomics is a genetics company developing a platform for individuals to get their personal genome sequenced, and then enable them to store and control that information through cryptographic encryption on the blockchain.

Key people:

4

Funding Rounds

$119.5m

Money raised

Wild Type is a San Francisco based company producing meat products like salmon using cellular agriculture lab techniques.

Key people:

8

Funding Rounds

$967.6m

Money raised

Freenome is a San Francisco-based company which uses genetic analysis for early cancer detection and risk assessment.

5

Funding Rounds

$155.6m

Money raised

Athelas is a company developing blood testing device that utilizes deep learning and computer vision.

4

Funding Rounds

$743.2m

Money raised

A bioinformatics company in San Francisco building data collection methods and databases that will enable machine learning algorithms in healthcare. It was founded in 2018.

1

Funding Rounds

$73.0m

Money raised

Antheia is an American biotechnology company founded in 2013, and is located in Menlo Park, California. Antheia uses synthetic biology, informatics, and fermentation technologies to produce plant based medicines; most notably opioids using yeast.

1

Funding Rounds

$750.0k

Money raised

Nextbiotics is a biotechnology and synthetic biology company that leverages synthetic biology tools and bacteriophage technology to provide solutions to the antibiotic resistance crisis.

8

Funding Rounds

$518.6m

Money raised

Cue Health is a San Diego-based medical device company working to track health information at the molecular level.

7

Funding Rounds

$249.0m

Money raised

Eko Health is a digital health and AI technology company developing tools for heart and lung disease detection.

Key people:

8

Funding Rounds

$100.4m

Money raised

A software-as-a-service technology company with a focus on robotic solutions for laboratories. It was founded in 2019 and is located in Menlo Park, California.

5

Funding Rounds

$27.5m

Money raised

Mission Barns is a clean meat company company is headquartered in Berkeley, California producing clean meat. The company was founded in March, 2018, by Eitan Fischer (former director of cellular agriculture of JUST, Inc) and David Bowman.

Key people:

1

Funding Rounds

$2.4m

Money raised

Bloom API is a healthcare company focused on communication practices.

4

Funding Rounds

$13.3m

Money raised

Fauna Bio is a Berkeley, California-based biotechnology company.

Key people:

3

Funding Rounds

$52.0m

Money raised

3T Biosciences is a biotechnology company developing immunotherapies.

4

Funding Rounds

$30.0m

Money raised

Company manufacturing 3d printed pharmaceuticals based in San Francisco, CA

Key people:

4

Funding Rounds

$87.8m

Money raised

DNA synthesis company using enzymatic DNA synthesis based in San Francisco.

2

Funding Rounds

$29.0m

Money raised

A company that develops next-generation sequencing (NGS) metagenomics company developing infectious disease tests. It was founded in 2014 and is located in Salt Late City, Utah.

4

Funding Rounds

$3.3m

Money raised

An enterprise software company developing computer aided design (CAD) tools for designing and testing DNA sequences.

Location:

Key people:

5

Funding Rounds

$24.1m

Money raised

BetterDoctor, a technology company, delivers provider directory data and has a database that can be accessed through a responsive API.

Key people:

3

Funding Rounds

$187.0m

Money raised

A company creating sustainable design solutions with biomaterials. It was founded in 2013 and is located in San Francisco, California.

1

Funding Rounds

$3.5m

Money raised

Biotechnology company using Artificial Intelligence to discover drugs by translating life sciences big data into therapies

3

Funding Rounds

$67.0m

Money raised

Faeth Therapeutics is a start-up that focuses on using nutrition and metabolism to fight cancer.

Location:

Key people:

5

Funding Rounds

$228.0m

Money raised

A biopharmaceutical company developing neurobehavioural therapeutic treatments using artificial intelligence and clinical neuroscience.

4

Funding Rounds

$205.5m

Money raised

Biotechnology company developing cell permeable macrocyclic peptide therapeutics using an automated chemistry synthesis.

13

Funding Rounds

$677.0m

Money raised

A gene editing technology company founded in 2015 and based in Boulder, CO, USA.

4

Funding Rounds

$16.8m

Money raised

YourChoice Therapeutics is a biotechnology company founded in 2018 is developing contraceptives for men and women. The technology for their non-hormonal contraceptive products arose from research at the University of California, Berkeley.

2

Funding Rounds

$30.0m

Money raised

Siolta Therapeutics develops microbiome analyses to test microbial-based therapeutics for the treatment and prevention of inflammatory diseases. The company was founded in 2016 by Nikole Kimes PhD.

2

Funding Rounds

$50.5m

Money raised

Memora Health is a company that created a health care productivity software that improves outpatient communication through automation.

Location:

Key people:

9

Funding Rounds

$617.8m

Money raised

Carbon Health is a healthcare company. They primarily serve California and the Reno area.

1

Funding Rounds

$150.0m

Money raised

Nobell Foods is a San Francisco-based alternative protein manufacturer focused on developing and manufacturing plant-based dairy alternatives.

Key people:

3

Funding Rounds

$59.5m

Money raised

64x Bio is a biotechnology company developing a platform for improving speed and scalability of mammalian cell line discovery for pharmaceutical and biotechnology companies.

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