62 Best Digital Health Startups in United States to Watch in 2025

The Definitive Seedtable Ranking of Digital Health Startups in United States

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 62 start-ups with an aggregate funding of $7.0b. The average funding per company in this subset is $112.1m.

Last update to the database: Feb 18, 2025. See changelog.

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10

Funding Rounds

$930.0m

Money raised

Tempus, a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

9

Funding Rounds

$276.0m

Money raised

A diagnostic DNA testing company using quantified biological data.

2

Funding Rounds

$158.0m

Money raised

Senti Biosciences is a synthetic biology company.

6

Funding Rounds

$399.8m

Money raised

Human Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived.

Key people:

3

Funding Rounds

$313.0m

Money raised

Flatiron Health is a startup that organizes real-time oncology data to help cancer patients and doctors.

6

Funding Rounds

$714.0m

Money raised

An insurance technology offering a platform for companies to manage health insurance policies for their employees.

7

Funding Rounds

$249.0m

Money raised

Eko Health is a digital health and AI technology company developing tools for heart and lung disease detection.

Key people:

3

Funding Rounds

$5.3m

Money raised

An insurance technology company offering a platform for healthcare organizations to access health insurance data to improve their ability to bring new products and services to market.

5

Funding Rounds

$24.1m

Money raised

BetterDoctor, a technology company, delivers provider directory data and has a database that can be accessed through a responsive API.

Key people:

1

Funding Rounds

$1.0m

Money raised

Choix is a telemedicine clinic providing reproductive and sexual healthcare.

1

Funding Rounds

$1.0m

Money raised

Sanguine is a company that has the mission to accelerate medical research by eliminating the barriers to patient participation.

5

Funding Rounds

$81.5m

Money raised

A blockchain platform for exchanging financial information without sharing data. It is located in Marina Del Rey, California and was founded in 2017.

Key people:

9

Funding Rounds

$617.8m

Money raised

Carbon Health is a healthcare company. They primarily serve California and the Reno area.

1

Funding Rounds

$1.8m

Money raised

An insurance technology company offering a telehealth platform for connecting doctors to employees through their company's health plan.

2

Funding Rounds

$25.2m

Money raised

Eligible is a medical billing company founded in 2011 that aims to make it easier for patients to predict how much their health insurance will pay and how much they will pay out of pocket prior to visiting their doctor.

5

Funding Rounds

$76.5m

Money raised

AllStripes is a U.S-based company offering a rare disease medical information database.

2

Funding Rounds

$24.0m

Money raised

Palo Alto, California-based Limbix is not your average virtual reality startup: It makes a software that therapists use in what's called "exposure therapy," simulating stressful or trauma-inducing situations for patients to help them overcome their fears.

4

Funding Rounds

$216.0m

Money raised

Alma's integrated Student Information System empowers learning communities with future-ready software created for today ... and tomorrow.

5

Funding Rounds

$12.0m

Money raised

BurstIQ is a company founded in 2015 by Frank Ricotta, Tyson Henry and Brian Jackson.

Key people:

5

Funding Rounds

$132.7m

Money raised

Notable Health is an artificial intelligence-powered health start up in California that focuses on automating and digitizing physician-patient interactions.

Key people:

7

Funding Rounds

$52.4m

Money raised

Protenus is a company that participated in the DreamIT Ventures - Health Baltimore 1/1/14 cohort .

5

Funding Rounds

$187.0m

Money raised

Iterative Health is a Cambridge, Massachusetts-based company that provides gastroenterologists with machine learning-powered diagnostic tools to aid in the prevention of colon cancer and improve patient outcomes.

10

Funding Rounds

$460.8m

Money raised

Aledade is a company founded in 2014.

7

Funding Rounds

$8.3m

Money raised

A startup company offering chairs and sofas designed for small apartments

Key people:

4

Funding Rounds

$18.9m

Money raised

A company offering a voice first care management platform that is headquartered in Boston, Massachusetts and was founded in 2014 by Dr. Aiden Feng, Emanuele Musini, and James Wyman.

2

Funding Rounds

$29.5m

Money raised

An insurance technology company offering a customer experience health insurance platform.

1

Funding Rounds

$6.0m

Money raised

CareMessage is a social enterprise providing a technology platform for health literacy and disease self-management for at-risk patient populations.

5

Funding Rounds

$151.0m

Money raised

Hello Heart is a company founded in 2013 by Ziv Meltzer.

Key people:

5

Funding Rounds

$103.0m

Money raised

VitalConnect is a wearable biosensor technology for wireless hospital and remote patient monitoring.

1

Funding Rounds

$2.3m

Money raised

Datica is a United States-based company founded by Sean Ironstag, Mohan Balachandran and Travis Good.

2

Funding Rounds

$92.9m

Money raised

The Pill Club is an company providing birth control services.

2

Funding Rounds

$95.0m

Money raised

Developer of a healthcare communications platform intended to connect doctors, nurses, care teams and patients on a common interface.

Key people:

5

Funding Rounds

$15.6m

Money raised

Everplans is a company offering end of life planning services founded in 2010 by Adam Seifer.

Key people:

2

Funding Rounds

Careport Health is a company founded in 2012 by Lissy Hu.

2

Funding Rounds

$65.0m

Money raised

AppliedVR is a company founded in 2015 by Matthew Stoudt.

2

Funding Rounds

$4.1m

Money raised

Paubox is a San Francisco-based company founded by Hoala Greevy.

5

Funding Rounds

$138.3m

Money raised

Biolinq, Inc. is a Needle-Free Blood Glucose Monitoring founded by Joshua Windmiller.

1

Funding Rounds

Company

1

Funding Rounds

$9.6m

Money raised

An elder care platform powered by voice and artificial intelligence technologies.

1

Funding Rounds

$12.8m

Money raised

The Helper Bees is a company founded by Danny Lynch, Char Hu and Eric Corum offering a platform for in-home elderly care.

Key people:

1

Funding Rounds

$5.0m

Money raised

Billy is a company making smart home technologies to help seniors live independently.

5

Funding Rounds

$410.3m

Money raised

Clarify Health Solutions is a company founded in 2015.

2

Funding Rounds

$12.5m

Money raised

Artificial Intelligence company

3

Funding Rounds

$20.5m

Money raised

Parachute Health is a company founded in 2015.

1

Funding Rounds

$4.0m

Money raised

Fit4D empoTheyrs and motivates diabetic patients towards optimal health and lifestyle through Theybinars, one-to-one virtual coaching, and more.

3

Funding Rounds

$6.6m

Money raised

Independa is a technology platform aiding elderly adults live independently founded in 2009.

3

Funding Rounds

$6.6m

Money raised

Orderly Health is an artificial Intelligence company founded in 2015 by Kevin Krauth.

Location:

Key people:

1

Funding Rounds

$600.0m

Money raised

Formerly ContextMedia, Outcome Health is a healthcare technology company developing and providing health intelligence technology solutions.

1

Funding Rounds

$12.0m

Money raised

NuvoAir is a company founded in 2016 by Lorenzo Consoli.

Key people:

2

Funding Rounds

$1.5m

Money raised

CoverUS is a blockchain company founded in 2018 by Peter Shanley, Christopher Sealey and Andrew Hoppin.

3

Funding Rounds

$18.5m

Money raised

MyHealthTeams is a company founded in 2012.

1

Funding Rounds

$1.8m

Money raised

A company providing a software platform for families to choose post-acute care providers during the hospital discharge process.

1

Funding Rounds

$6.5m

Money raised

Worklete is a company founded by Benjamin Kanner.

1

Funding Rounds

$43.0m

Money raised

MedTrainer operates as a healthcare-focused compliance management suite.

1

Funding Rounds

$21.0m

Money raised

Glytec is a predictive dosing algorithm for diabetes founded in 2006.

1

Funding Rounds

$10.3m

Money raised

A company offering end of life services that is headquartered in Palo Alto, California.

2

Funding Rounds

$13.0m

Money raised

Murj is a United States-based company.

2

Funding Rounds

$32.7m

Money raised

Stork Club is a company founded in 2018 by Jeni Mayorskaya.

Key people:

3

Funding Rounds

$9.0m

Money raised

Carepoynt is a United States-based company founded in 2018.

1

Funding Rounds

Kolkin is a United States-based company founded by Auron Priestley.

1

Funding Rounds

$30.0k

Money raised

PT PAL is a company founded in 2013.

1

Funding Rounds

$7.0m

Money raised

Datos Health is a company founded by Uri Bettesh.

Location:

Key people:

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