69 Best Big Data Startups in United States to Watch in 2025

The Definitive Seedtable Ranking of Big Data Startups in United States

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 92 start-ups with an aggregate funding of $9.3b. The average funding per company in this subset is $135.1m.

Last update to the database: Feb 18, 2025. See changelog.

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10

Funding Rounds

$1.0b

Money raised

DataRobot sells a machine learning platform that helps users build and deploy accurate predictive models. The Boston-based company was founded in 2012 by Jeremy Achin.

8

Funding Rounds

$390.0m

Money raised

Exabeam is a San Mateo, California-based data security analytics company offering cybersecurity and early cyber attack detection software.

6

Funding Rounds

$100.9m

Money raised

AppZen is a San Jose, California-based company that provides an AI-based auditing platform for finance teams.

Key people:

10

Funding Rounds

$930.0m

Money raised

Tempus, a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

3

Funding Rounds

$125.0m

Money raised

Synchron, Inc. is a technology company building implantable neural interface solutions, including endovascular brain-computer interface.

7

Funding Rounds

$314.2m

Money raised

HawkEye 360 is a Herndon, Virginia-based data analytics company developing radio frequency mapping technologies for use in space.

Key people:

3

Funding Rounds

$14.3m

Money raised

Aria Pharmaceuticals is a first-in-class pharmaceutical discovery and development founded in 2014 by Andrew M. Radin.

3

Funding Rounds

$313.0m

Money raised

Flatiron Health is a startup that organizes real-time oncology data to help cancer patients and doctors.

2

Funding Rounds

$300.0m

Money raised

ClickHouse is an open-source database management software developed originally by Yandex before being incorporated in 2021 by Aaron Katz, Alexey Milovidov, and Yury Izrailevsky.

Key people:

7

Funding Rounds

$1.5b

Money raised

Dataminr is a company providing a real-time AI platform delivering information on high-impact events and breaking news.

Key people:

5

Funding Rounds

$2.3m

Money raised

An app that aggregates social media data to produce a real-time map of sickness.

3

Funding Rounds

$4.1m

Money raised

Analytical Space is a satellite communications company making satellites equipped with RD-laser communications technology.

5

Funding Rounds

$33.9m

Money raised

A company building an identity resolution & insights platform

3

Funding Rounds

$54.1k

Money raised

ApexQubit is a biotechnology company that is harnessing a proprietary technology for discovery of new medicines to treat patients with undruggable diseases.

2

Funding Rounds

$23.6m

Money raised

Molecula is a data virtualization company that enables instantaneous, secure access to large, fragmented and geographically dispersed datasets to support demanding Machine Learning (ML) and Artificial Intelligence (AI) workloads.

Key people:

15

Funding Rounds

$249.8m

Money raised

Sift Science is a San Francisco-based company founded in 2011 by Brandon Ballinger.

12

Funding Rounds

$296.1m

Money raised

BigID is a cybersecurity company developing a platform for data protection and privacy compliance.

Key people:

7

Funding Rounds

$24.0m

Money raised

Headset is a tech company providing an IT solution for the cannabis industry.

Key people:

3

Funding Rounds

$5.3m

Money raised

An insurance technology company offering a platform for healthcare organizations to access health insurance data to improve their ability to bring new products and services to market.

5

Funding Rounds

$24.1m

Money raised

BetterDoctor, a technology company, delivers provider directory data and has a database that can be accessed through a responsive API.

Key people:

3

Funding Rounds

$144.0m

Money raised

An insurance technology company offering a software platform for life insurance.

3

Funding Rounds

$62.0m

Money raised

A software company offering an open-source platform for machine learning and data science teams to create data applications with python.

2

Funding Rounds

$5.0m

Money raised

CompStak is a company founded in 2011 by Vadim Belobrovka.

9

Funding Rounds

$969.3m

Money raised

Farmers Business Network is a company that utilizes data to provide enterprise solutions for farmers.

8

Funding Rounds

$33.8m

Money raised

Apptopia is a company founded in 2011 by Eliran Sapir.

2

Funding Rounds

$25.2m

Money raised

Eligible is a medical billing company founded in 2011 that aims to make it easier for patients to predict how much their health insurance will pay and how much they will pay out of pocket prior to visiting their doctor.

1

Funding Rounds

Spero Foods is a food and data analytics company located in Los Angeles, California, founded in 2016 by Phaedra Anestassia using data analytics to make plant-based diary and egg alternatives.

8

Funding Rounds

$276.2m

Money raised

Feedzai is a San Mateo, California-based Information Technology & Services company.

Key people:

5

Funding Rounds

$120.2m

Money raised

Crossbeam is a collaborative data platform that helps companies build more valuable partnerships.

Key people:

3

Funding Rounds

$1.5m

Money raised

MixRank is a company providing lead generation service for businesses. It utilizes LiveScan Contacts Engine together with mobile and web intelligence for lead generation automation.

4

Funding Rounds

$44.0m

Money raised

ShareThis is a company founded in 2007.

2

Funding Rounds

$14.0m

Money raised

A biotechnology company using the environmental microbiome to verify the origin of goods in global supply chains.

1

Funding Rounds

$6.5m

Money raised

Fluree is a Winston Salem, NC-based company developing a web3 data platform.

11

Funding Rounds

$528.2m

Money raised

Stem is a Millbrae, California-based developer of solutions for energy consumption through a combination of data, predictive analytics, and energy storage to reduce energy costs.

8

Funding Rounds

$113.7m

Money raised

Agari is a Foster City, California-based cybersecurity company using artificial intelligence for the provision of email threat prevention and protection.

2

Funding Rounds

$607.2k

Money raised

An insurance technology company offering software for life insurance management.

3

Funding Rounds

$2.5m

Money raised

Pigeonly is a company offering a subscrition-based platform for searching, finding and communicating with incarcerated people.

5

Funding Rounds

$8.3m

Money raised

Skyward developed an operations management solution for commercial drone businesses. Acquired by Verizon.

Location:

Key people:

1

Funding Rounds

$1.5m

Money raised

Pixlee is a company founded in 2012 by Kyle Wong, Miraj Mohsin, Jeff Zhifan Chen and Awad Sayeed.

Key people:

1

Funding Rounds

$6.0m

Money raised

A software company creating cloud-based enterprise insurance management software.

2

Funding Rounds

$1.3m

Money raised

Reesio is a company founded in 2012 by Uyen Tran, Jonathan Mui, John Dulay and Mark Thomas.

2

Funding Rounds

Beacon AI is a San Francisco-based company building an AI Copilot to enable flight safety for commercial and private fleets.

1

Funding Rounds

$6.0m

Money raised

CareMessage is a social enterprise providing a technology platform for health literacy and disease self-management for at-risk patient populations.

5

Funding Rounds

$685.0m

Money raised

Fractal Analytics is a United States-based analytics company founded in 2000

Location:

Key people:

2

Funding Rounds

$2.7m

Money raised

PredictionIO is a company that offers a machine learning open source stack.

3

Funding Rounds

$8.2m

Money raised

Packback is a company founded in 2014 by Nick Currier, Kasey Gandham, Jessica Tenuta and Mike Shannon.

Key people:

1

Funding Rounds

$19.0m

Money raised

A company offering a platform for helping people make health plan decisions.

Key people:

1

Funding Rounds

$2.3m

Money raised

Datica is a United States-based company founded by Sean Ironstag, Mohan Balachandran and Travis Good.

1

Funding Rounds

$300.0k

Money raised

Prifina is a blockchain company founded in 2018 by Valto Loikkanen, Markus Lampinen and Jouko Ahvenainen.

Industries:

Key people:

7

Funding Rounds

$13.1m

Money raised

ROSS Intelligence is a company offering an artificial intelligent system for legal research.

4

Funding Rounds

$35.0m

Money raised

Baffle.io provides cloud database encryption for increased security.

2

Funding Rounds

$95.0m

Money raised

Developer of a healthcare communications platform intended to connect doctors, nurses, care teams and patients on a common interface.

Key people:

1

Funding Rounds

$1.1m

Money raised

OLSET is a company founded in 2012 by Gadi Bashvitz.

Key people:

8

Funding Rounds

$35.4m

Money raised

Hydrosat is a company founded in 2017.

5

Funding Rounds

$14.0m

Money raised

Inpher is an analytics company.

4

Funding Rounds

$3.5m

Money raised

MoBagel is an artificial Intelligence company founded in 2009 by Iru Wang, Adms Chung and Ken Lin.

4

Funding Rounds

$17.0m

Money raised

Saltbox is a purpose-built workspace for companies that need warehouse and coworking space. Located in Atlanta, Saltbox provides shared workspace for commerce sellers, distributors, makers or any entrepreneur that work with physical goods.

3

Funding Rounds

$91.0m

Money raised

Morning Consult is a global decision intelligence company changing how modern leaders make smarter, faster, and better decisions.

Key people:

2

Funding Rounds

ScoreData is a company that offers an innovative predictive solutions development and deployment platform.

4

Funding Rounds

$54.5m

Money raised

DataVisor is a researching and developing company with focus in fraud management.

Key people:

4

Funding Rounds

$19.0m

Money raised

Operator of an AI-driven construction-planning technology company designed for digitization in the construction industry. The company offers an efficient, advanced, and scalable service using artificial intelligence and data-driven methodologies.

2

Funding Rounds

$4.1m

Money raised

Paubox is a San Francisco-based company founded by Hoala Greevy.

7

Funding Rounds

$36.5m

Money raised

Wyng is a company founded in 2010 by Wendell Lansford, Allen Bonde, Prakash Mishra and Mark Cooper.

2

Funding Rounds

$88.0m

Money raised

Ceribel is a Sunnyvale, California-based medical device company aiming to improve neurological care for emergency and ICU patients by making electroencephalogram (EEG) technology more accessible and efficient.

1

Funding Rounds

$8.0m

Money raised

A data analytics company for insurers and multi-national industrial companies.

4

Funding Rounds

$2.8m

Money raised

Seeloz is a company that uses Artificial Intelligence to help organizations develop supply chain value.

6

Funding Rounds

$6.7m

Money raised

BrightBytes is a company founded in 2012 by Rob Mancabelli.

3

Funding Rounds

$65.0m

Money raised

Securonix delivers a security analytics and operations management platform for the modern era of big data and advanced cyber threats.

1

Funding Rounds

$100.0k

Money raised

LearnMetrics is a company founded in 2012 by Julian Miller, Matt Duch and Brian Dellabetta.

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